CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024282
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Solute carrier family 22 member 23 
Protein Synonyms/Alias
  
Gene Name
 SLC22A23 
Gene Synonyms/Alias
 C6orf85 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
133FWCRGAGKGTELAGVubiquitination[1]
684GATANGMKAM*****ubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
 CARBOHYD 24 24 N-linked (GlcNAc...) (Potential).
 CARBOHYD 279 279 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 686 AA 
Protein Sequence
MAIDRRREAA GGGPGRQPAP AEENGSLPPG DAAASAPLGG RAGPGGGAEI QPLPPLHPGG 60
GPHPSCCSAA AAPSLLLLDY DGSVLPFLGG LGGGYQKTLV LLTWIPALFI GFSQFSDSFL 120
LDQPNFWCRG AGKGTELAGV TTTGRGGDMG NWTSLPTTPF ATAPWEAAGN RSNSSGADGG 180
DTPPLPSPPD KGDNASNCDC RAWDYGIRAG LVQNVVSKWD LVCDNAWKVH IAKFSLLVGL 240
IFGYLITGCI ADWVGRRPVL LFSIIFILIF GLTVALSVNV TMFSTLRFFE GFCLAGIILT 300
LYALRIELCP PGKRFMITMV ASFVAMAGQF LMPGLAALCR DWQVLQALII CPFLLMLLYW 360
SIFPESLRWL MATQQFESAK RLILHFTQKN RMNPEGDIKG VIPELEKELS RRPKKVCIVK 420
VVGTRNLWKN IVVLCVNSLT GYGIHHCFAR SMMGHEVKVP LLENFYADYY TTASIALVSC 480
LAMCVVVRFL GRRGGLLLFM ILTALASLLQ LGLLNLIGKY SQHPDSGMSD SVKDKFSIAF 540
SIVGMFASHA VGSLSVFFCA EITPTVIRCG GLGLVLASAG FGMLTAPIIE LHNQKGYFLH 600
HIIFACCTLI CIICILLLPE SRDQNLPENI SNGEHYTRQP LLPHKKGEQP LLLTNAELKD 660
YSGLHDAAAA GDTLPEGATA NGMKAM 686 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
 GO:0006811; P:ion transport; IEA:UniProtKB-KW. 
Interpro
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR005829; Sugar_transporter_CS. 
Pfam
 PF00083; Sugar_tr 
SMART
  
PROSITE
 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1 
PRINTS