UniProt Accession

 A3R404_MOUSE; A3R404 

Genbank Protein ID

 EF108338; HQ675026; HQ675027; HQ675028; HQ675029; HQ675030; HQ675031 

Genbank Nucleotide ID

 ABK79201.1; AEN03373.1; AEN03386.1; AEN03399.1; AEN03412.1; AEN03425.1; AEN03438.1 

Protein Name

 ATP synthase protein 8 

Protein Synonyms/Alias

  

Gene Name

 mt-Atp8 

Gene Synonyms/Alias

 ATP8; mt-Atp6 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
57	PWELKWTKIYLPHSL	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity). 

Sequence Annotation

  

Keyword

 ATP synthesis; CF(0); Hydrogen ion transport; Hydrolase; Ion transport; Membrane; Mitochondrion; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 67 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IEA:InterPro.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. 

Interpro

 IPR001421; ATPase_F0-cplx_su8_mt_metazoan. 

Pfam

 PF00895; ATP-synt_8 

SMART

  

PROSITE

  

PRINTS