CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025046
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chaperonin containing Tcp1, subunit 6A (Zeta 1) 
Protein Synonyms/Alias
 Chaperonin subunit 6a (Zeta); Protein Cct6a 
Gene Name
 Cct6a 
Gene Synonyms/Alias
 rCG_21714 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
5***MAAVKTLNPKAEacetylation[1]
127TEGFEAAKEKALQFLacetylation[1]
141LEQVKVSKEMDRETLacetylation[1]
295GFVVINQKGIDPFSLacetylation[1]
307FSLDALAKEGIVALRacetylation[1]
377RSVTLLVKGPNKHTLubiquitination[2]
381LLVKGPNKHTLTQIKacetylation[1]
388KHTLTQIKDAIRDGLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Cytoplasm; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 531 AA 
Protein Sequence
MAAVKTLNPK AEVARAQAAL AVNISAARGL QDVLRTNLGP KGTMKMLVSG AGDIKLTKDG 60
NVLLHEMQIQ HPTASLIAKV ATAQDDITGD GTTSNVLIIG ELLKQADLYI SEGLHPRIIT 120
EGFEAAKEKA LQFLEQVKVS KEMDRETLID VARTSLRTKV HAELADVLTE AVVDSILAIR 180
KKDEPIDLFM VEIMEMKHKS ETDTSLIRGL VLDHGARHPD MKKRVENAYI LTCNVSLEYE 240
KTEVNSGFFY KSAEEREKLV KAERKFIEDR VKKIVELKKK VCGDSDKGFV VINQKGIDPF 300
SLDALAKEGI VALRRAKRRN MERLTLACGG IALNSFDDLN PDCLGHAGLV YEYTLGEEKF 360
TFIEKCNNPR SVTLLVKGPN KHTLTQIKDA IRDGLRAVKN AIDDGCVVPG AGAVEVALAE 420
ALIKYKPSVK GRAQLGVQAF ADALLIIPKV LAQNSGFDLQ ETLVKVQAEH SESGQLVGVD 480
LNTGEPMVAA EMGVWDNYCV KKQLLHSCTV IATNILLVDE IMRAGMSSLK G 531 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR012722; Chap_CCT_zeta.
 IPR017998; Chaperone_TCP-1.
 IPR002194; Chaperonin_TCP-1_CS.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial.
 IPR027410; TCP-1-like_intermed. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00750; TCP1_1
 PS00751; TCP1_2
 PS00995; TCP1_3 
PRINTS
 PR00304; TCOMPLEXTCP1.