CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024556
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 EF-hand calcium-binding domain-containing protein 7 
Protein Synonyms/Alias
  
Gene Name
 EFCAB7 
Gene Synonyms/Alias
 KIAA1799 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
15DATFSSQKSTPSESPubiquitination[1]
57SLENIISKDQLYLALubiquitination[1]
100CIILRKEKPTSKAELubiquitination[1]
104RKEKPTSKAELLKSFubiquitination[1]
109TSKAELLKSFKQLDVubiquitination[1]
112AELLKSFKQLDVNDDubiquitination[1]
165FDYIKFCKLYMTTNEubiquitination[1]
210RDPSPVPKPSPKITRubiquitination[1]
227DPETFLNKGDTRSSLubiquitination[1]
439ELRTSGEKCDEDAWAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 DOMAIN 102 137 EF-hand 1.
 DOMAIN 138 173 EF-hand 2.
 DOMAIN 403 438 EF-hand 3.  
Keyword
 Alternative splicing; Calcium; Complete proteome; Metal-binding; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 629 AA 
Protein Sequence
MAISPRSDAT FSSQKSTPSE SPRTKKFPLT EEEIFYMNCR AAYLTVFKSS LENIISKDQL 60
YLALQHAGRN PSQKTINKYW TPQTAKLNFD DFCIILRKEK PTSKAELLKS FKQLDVNDDG 120
CILHTDLYKF LTKRGEKMTR EEVNAIINLA DVNADGKFDY IKFCKLYMTT NEQCLKTTLE 180
KLEVDSKLMR HQFGNHIEGS PERDPSPVPK PSPKITRKTD PETFLNKGDT RSSLLSATRK 240
FKTSVSFTVT MGANGNRNSK LMEPNLIKDW QHMQSKGCFF LEEDGEIISH QYRMQIAQRS 300
MVYLTIKPLN LSQVEGKPSP WLSVDTALYI LKENESQANL QLVCFTELRN REVFGWTGEL 360
GPGIYWLIPS TTGCRLRKKI KPVTDEAQLV YRDETGELFL TKEFKSTLSD IFEVIDLDGN 420
GLLSLEEYNF FELRTSGEKC DEDAWAVCRE NFDTKRNELT RQGFMDLNLM EANDREGDPC 480
DLWVTLHSMG YNKALELTEA CPFVIDIYAE KCKPKIKAVH MEACSGQLEK AICKSVLSNG 540
DAKVMDGYEN IIVHTYSCDT WITSVIENKS DEKVIIHISN ELSKNCINNR GLNIFAVEVG 600
PKSTMVCQHV MPLNERQEWI YYCIYSLIS 629 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF13202; EF_hand_3
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS