CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-027247
UniProt Accession
Q8C5K4_MOUSE
;
Q8C5K4
Genbank Protein ID
AK078167
Genbank Nucleotide ID
BAC37157.1
Protein Name
Microtubule-associated protein
Protein Synonyms/Alias
Gene Name
Mapt
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Lysine Modification
Position
Peptide
Type
References
62
GSVQIVY
K
PVDLSKV
ubiquitination
[1]
Reference
[1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [
PMID: 22790023
]
Functional Description
Sequence Annotation
Keyword
Microtubule; Repeat.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
192 AA
Protein Sequence
MPDLKNVRSK IGSTENLKHQ PGGGKVQIIN KELDLSTVQS KCGSKDNIKH VPGRGSVQIV 60
YKPVDLSKVT SKCGSLGNIH HKPGGGQVEV KSEKLDFKDR VQSKIGSLDN ITHVPGGGNK 120
KIETHKLTFR ENAKAKTDHG AEIVYKSPVV SGDTSPRHLS NVSSTGSIDM VDSPQLATLA 180
DEVSASLAKQ GL 192
Gene Ontology
GO:0030424
; C:axon; IDA:MGI.
GO:0035085
; C:cilium axoneme; IDA:MGI.
GO:0005874
; C:microtubule; IDA:MGI.
GO:0005634
; C:nucleus; IDA:MGI.
GO:0008017
; F:microtubule binding; IDA:MGI.
GO:0007628
; P:adult walking behavior; IGI:MGI.
GO:0008088
; P:axon cargo transport; IGI:MGI.
GO:0048675
; P:axon extension; IMP:MGI.
GO:0000226
; P:microtubule cytoskeleton organization; IMP:MGI.
GO:0047497
; P:mitochondrion transport along microtubule; IMP:MGI.
GO:0032387
; P:negative regulation of intracellular transport; IMP:MGI.
GO:0001764
; P:neuron migration; IMP:MGI.
GO:0045773
; P:positive regulation of axon extension; IMP:MGI.
GO:0060632
; P:regulation of microtubule-based movement; IDA:MGI.
Interpro
IPR027324
; MAP2/MAP4/Tau.
IPR001084
; Tau/MAP_tubulin-bd_rpt.
Pfam
PF00418
; Tubulin-binding
SMART
PROSITE
PS00229
; TAU_MAP_1
PS51491
; TAU_MAP_2
PRINTS