CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001338
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable histone H2A.3 
Protein Synonyms/Alias
 HTA2 
Gene Name
 At4g27230; M4I22.40 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
6**MAGRGKQLGSGAAacetylation[1]
Reference
 [1] Distinctive core histone post-translational modification patterns in Arabidopsis thaliana.
 Zhang K, Sridhar VV, Zhu J, Kapoor A, Zhu JK.
 PLoS One. 2007 Nov 21;2(11):e1210. [PMID: 18030344
Functional Description
 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. 
Sequence Annotation
  
Keyword
 Chromosome; Complete proteome; DNA-binding; Nucleosome core; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 131 AA 
Protein Sequence
MAGRGKQLGS GAAKKSTSRS SKAGLQFPVG RIARFLKAGK YAERVGAGAP VYLAAVLEYL 60
AAEVLELAGN AARDNKKTRI VPRHIQLAVR NDEELSKLLG DVTIANGGVM PNIHNLLLPK 120
KAGSSKPTEE D 131 
Gene Ontology
 GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IDA:TAIR.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 
Interpro
 IPR009072; Histone-fold.
 IPR007125; Histone_core_D.
 IPR002119; Histone_H2A. 
Pfam
 PF00125; Histone 
SMART
 SM00414; H2A 
PROSITE
 PS00046; HISTONE_H2A 
PRINTS
 PR00620; HISTONEH2A.