CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037955
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 UBX domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 UBXN1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
289SAVLIVAKKCPS***ubiquitination[1, 2, 3]
290AVLIVAKKCPS****ubiquitination[4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 293 AA 
Protein Sequence
MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLETPLGHIL 60
GREPTSSEQG GLEGSGSAAG EGKPALSEEE RQEQTKRMLE LVAQKQRERE EREEREALER 120
ERQRRRQGQE LSAARQRLQE DEMRRAAEER RREKAEEQRV REKIERDKAE RAKKYGGSVG 180
SQPPPVAPEP GPVPSSPSQE PPTKREYDQC RIQVRLPDGT SLTQTFRARE QLAAVRLYVE 240
LHRGEELGGG QDPVQLLSGF PRRAFSEADM ERPLQELGLV PSAVLIVAKK CPS 293 
Gene Ontology
  
Interpro
 IPR009060; UBA-like.
 IPR000449; UBA/transl_elong_EF1B_N.
 IPR015940; UBA/transl_elong_EF1B_N_euk.
 IPR001012; UBX. 
Pfam
 PF00627; UBA
 PF00789; UBX 
SMART
 SM00165; UBA
 SM00166; UBX 
PROSITE
 PS50030; UBA
 PS50033; UBX 
PRINTS