CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002771
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycerophosphoryl diester phosphodiesterase 
Protein Synonyms/Alias
 Glycerophosphodiester phosphodiesterase 
Gene Name
 glpQ 
Gene Synonyms/Alias
 b2239; JW2233 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
319PYTVRSDKLPEYTPDacetylation[1]
350LFTDFPDKAVKFLNKacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. 
Sequence Annotation
 METAL 63 63 Calcium.
 METAL 65 65 Calcium.
 METAL 171 171 Calcium.  
Keyword
 3D-structure; Calcium; Complete proteome; Direct protein sequencing; Glycerol metabolism; Hydrolase; Metal-binding; Periplasm; Reference proteome; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 358 AA 
Protein Sequence
MKLTLKNLSM AIMMSTIVMG SSAMAADSNE KIVIAHRGAS GYLPEHTLPA KAMAYAQGAD 60
YLEQDLVMTK DDNLVVLHDH YLDRVTDVAD RFPDRARKDG RYYAIDFTLD EIKSLKFTEG 120
FDIENGKKVQ TYPGRFPMGK SDFRVHTFEE EIEFVQGLNH STGKNIGIYP EIKAPWFHHQ 180
EGKDIAAKTL EVLKKYGYTG KDDKVYLQCF DADELKRIKN ELEPKMGMEL NLVQLIAYTD 240
WNETQQKQPD GSWVNYNYDW MFKPGAMKQV AEYADGIGPD YHMLIEETSQ PGNIKLTGMV 300
QDAQQNKLVV HPYTVRSDKL PEYTPDVNQL YDALYNKAGV NGLFTDFPDK AVKFLNKE 358 
Gene Ontology
 GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
 GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:EC.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
 GO:0006629; P:lipid metabolic process; IEA:InterPro. 
Interpro
 IPR004129; GlyceroP-diester-Pdiesterase.
 IPR017946; PLC-like_Pdiesterase_TIM-brl. 
Pfam
 PF03009; GDPD 
SMART
  
PROSITE
  
PRINTS