UniProt Accession

 F5GZ99_HUMAN; F5GZ99 

Genbank Protein ID

 AC005844; AC007406 

Genbank Nucleotide ID

  

Protein Name

 Lysine-specific demethylase 5A 

Protein Synonyms/Alias

  

Gene Name

 KDM5A 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
86	ELEIVASKGGFEMVT	ubiquitination	[1]
94	GGFEMVTKEKKWSKV	ubiquitination	[1]
96	FEMVTKEKKWSKVGS	ubiquitination	[1]
111	RLGYLPGKGTGSLLK	ubiquitination	[1, 2, 3]
118	KGTGSLLKSHYERIL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 126 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:InterPro. 

Interpro

 IPR001606; ARID/BRIGHT_DNA-bd.
 IPR003349; TF_JmjN. 

Pfam

 PF01388; ARID
 PF02375; JmjN 

SMART

 SM00545; JmjN 

PROSITE

 PS51011; ARID
 PS51183; JMJN 

PRINTS