CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035328
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Membrane associated guanylate kinase, WW and PDZ domain containing 2, isoform CRA_a 
Protein Synonyms/Alias
 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 
Gene Name
 Magi2 
Gene Synonyms/Alias
 rCG_24428 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
258TRDASQLKGTFLSTTubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1114 AA 
Protein Sequence
MELEKSGALL ESGTYEDNYY GTPKPPAEPA PLLLNVTDQI LPGATPSAEG KRKRNKSVTN 60
MEKASIEPPE EEEEERPVVN GNGVVITPES SEHEDKSAGA SGETPSQPYP APVYSQPEEL 120
KDQMDDTKST KPEENEDSDP LPDNWEMAYT EKGEVYFIDH NTKTTSWLDP RLAKKAKPAE 180
ECKENELPYG WEKIDDPIYG TYYVDHINRR TQFENPVLEA KRKLQQHNMP HTELGTKPLQ 240
APGFREKPLF TRDASQLKGT FLSTTLKKSN MGFGFTIIGG DEPDEFLQVK SVIPDGPAAQ 300
DGKMETGDVI VYINEVCVLG HTHADVVKLF QSVPIGQSVN LVLCRGYPLP FDPEDPANSM 360
VPPLAIMERP PPVMVNGRHN YETYLEYISR TSQSVPDITD RPPHSLHSMP ADGQLDGTYP 420
PPVHDDNVSV ASSGATQAEL MTLTIVKGAQ GFGFTIADSP TGQRVKQILD IQGCPGLCEG 480
DLIVEINQQN VQNLSHTEVV DILKDCPVGS ETSLIIHRGG FFSPWKTPKP MVDRWENQGS 540
PQTSLSAPAV PQSLPFPPAL HRSSFPDSTE AFDPRKPDPY ELYEKSRAIY ESRQQVPPRT 600
SFRMDSSGPD YKELDVHLRR MESGFGFRIL GGDEPGQPIL IGAVIAMGSA DRDGRLHPGD 660
ELVYVDGIPV AGKTHRYVID LMHHAARNGQ VNLTVRRKVL CGGEPCPENG RSPGSVSTHH 720
SSPRSDYATY ANSNHAAPSS NASPPEGFAS HSLQTSDVII HRKENEGFGF VIISSLNRPE 780
SGATITVPHK IGRIIDGSPA DRCAKLKVGD RILAVNGQSI INMPHADIVK LIKDAGLSVT 840
LRIIPQEELN SPTSAPSSEK QSPMAQQHSP LAQQHSPLAQ PSPATPNSPV AQPAPPQPLQ 900
LQGHENSYRS EVKARQDVKP DIRQPPFTDY RQPPLDYRQP PGGDYSQPSP LDYRQHSPDT 960
RQYPLSDYRQ PQDFDYFTVD MEKGAKGFGF SIRGGREYKM DLYVLRLAED GPAIRNGRMR 1020
VGDQIIEING ESTRDMTHAR AIELIKSGGR RVRLLLKRGT GQVPEYGMVP SSLSMCMKSD 1080
KHGSPYFYLL GHPKDTTNPT PGALPLPPPQ ACRK 1114 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005923; C:tight junction; IEA:Compara.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0004871; F:signal transducer activity; IEA:Compara.
 GO:0032926; P:negative regulation of activin receptor signaling pathway; IEA:Compara.
 GO:0051898; P:negative regulation of protein kinase B signaling cascade; IEA:Compara.
 GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IEA:Compara.
 GO:0002092; P:positive regulation of receptor internalization; IEA:Compara.
 GO:0060395; P:SMAD protein signal transduction; IEA:Compara. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR001478; PDZ.
 IPR001202; WW_dom. 
Pfam
 PF00595; PDZ
 PF00397; WW 
SMART
 SM00228; PDZ
 SM00456; WW 
PROSITE
 PS50106; PDZ
 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2 
PRINTS