CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028621
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cohesin subunit SA-2 
Protein Synonyms/Alias
  
Gene Name
 Stag2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
270RLELLLQKRKELQENubiquitination[1]
607YTTGRLEKHLDALLRacetylation[2]
965TFGLDQLKTREAIAMubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1268 AA 
Protein Sequence
MIAAPEIPTD FNLLQESETH FSSDTDFEDI EGKNQKQGKG KTCKKGKKGP AEKGKSGNGG 60
GKPPSGSNRM NGHHQQNGVE NMMLFEVVKM GKSAMQSVVD DWIESYKHDR DIALLDLINF 120
FIQCSGCKGV VTAEMFRHMQ NSEIIRKMTE EFDEDSGDYP LTMAGPQWKK FKSSFCEFIG 180
VLVRQCQYSI IYDEYMMDTV ISLLTGLSDS QVRAFRHTST LAAMKLMTAL VNVALNLSIN 240
MDNTQRQYEA ERNKMIGKRA NERLELLLQK RKELQENQDE IENMMNAIFK GVFVHRYRDA 300
IAEIRAICIE EIGIWMKMYS DAFLNDSYLK YVGWTMHDKQ GEVRLKCLTA LQGLYYNKEL 360
NSKLELFTSR FKDRIVSMTL DKEYDVAVQA IKLLTLVLQS SEEVLTAEDC ENVYHLVYSA 420
HRPVAVAAGE FLYKKLFSRR DPEEDGLMKR RGRQGPNANL VKTLVFFFLE SELHEHAAYL 480
VDSMWDCATE LLKDWECMNS LLLEEPLSGE EALTDRQESA LIEIMLCTIR QAAECHPPVG 540
RGTGKRVLTA KEKKTQLDDR TRITELFAVA LPQLLAKYSV DAEKVTNLLQ LPQYFDLEIY 600
TTGRLEKHLD ALLRQIRNIV EKHTDTDVLE ACSKTYHALC NEEFTIFNRV DISRSQLIDE 660
LADKFNRLLE DFLQEGEEPD EDDAYQVLST LKRITAFHNA HDLSKWDLFA CNYKLLKTGI 720
ENGDMPEQIV IHALQCAHYV ILWQLAKITE STSTKEDLLR LKKQMRVFCQ ICQHYLTNVN 780
TTVKEQAFTI LCDILMIFSH QIMSGGRDML EPLVYTPDSS LQSELLSFIL DHVFIEQDDD 840
SNSADGQQED EASKIEALHK RRNLLAAFCK LIVYTVVEMN TAADIFKQYM KYYNDYGDII 900
KETMSKTRQI DKIQCAKTLI LSLQQLFNEM IQENGYNFDR SSSTFSGIKE LARRFALTFG 960
LDQLKTREAI AMLHKDGIEF AFKEPNPQGE SHPPLNLAFL DILSEFSSKL LRQDKRTVYV 1020
YLEKFMTFQM SLRREDVWLP LMSYRNSLLA GGDDDTMSVI SGMSSRGSTV RSKKSKPSTG 1080
KRKVVEGMQL ALPEESSSSD SMWLSREQTL HTPVMMQTPQ LTSTIMREPK RLRPEDSFMS 1140
VYPMQAEHHQ TPLDYNTQVT WMLAQRQQEE ARQQQERAAM SYVKLRTNLQ HAIRRGTSLM 1200
EDDEEPIVED VMMSSEGRIE DLNEGMDFDT MDIDLPPSKN RRERTELKPD FFDPASIMDE 1260
SVLGVSMF 1268 
Gene Ontology
 GO:0019827; P:stem cell maintenance; IMP:MGI. 
Interpro
 IPR016024; ARM-type_fold.
 IPR020839; SCD.
 IPR013721; STAG. 
Pfam
 PF08514; STAG 
SMART
  
PROSITE
 PS51425; SCD 
PRINTS