CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024483
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Maestro heat-like repeat-containing protein family member 6 
Protein Synonyms/Alias
  
Gene Name
 MROH6 
Gene Synonyms/Alias
 C8orf73 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
51QPKSWEVKPEAEPQTubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
 REPEAT 356 393 HEAT 1.
 REPEAT 397 434 HEAT 2.
 REPEAT 436 473 HEAT 3.
 REPEAT 477 514 HEAT 4.
 REPEAT 527 563 HEAT 5.
 REPEAT 594 631 HEAT 6.
 REPEAT 633 674 HEAT 7.  
Keyword
 Complete proteome; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 719 AA 
Protein Sequence
MAGGVWGRSR AREAPVGALT LTALTEGIRA RQGQPQGPPS AGPQPKSWEV KPEAEPQTQA 60
LTAPSEAEPG RGATVPEAGS EPCSLNSALE PAPEGPHQVP QSSWEEGVLA DLALYTAACL 120
EEAGFAGTQA TVLTLSSALE ARGERLEDQV HALVRGLLAQ VPSLAEGRPW RAALRVLSAL 180
ALEHARDVVC ALLPRSLPAD RVAAELWRSL SRNQRVNGQV LVQLLWALKG ASGPEPQALA 240
ATRALGEMLA VSGCVGATRG FYPHLLLALV TQLHKLARSP CSPDMPKIWV LSHRGPPHSH 300
ASCAVEALKA LLTGDGGRMV VTCMEQAGGW RRLVGAHTHL EGVLLLASAM VAHADHHLRG 360
LFADLLPRLR SADDPQRLTA MAFFTGLLQS RPTARLLREE VILERLLTWQ GDPEPTVRWL 420
GLLGLGHLAL NRRKVRHVST LLPALLGALG EGDARLVGAA LGALRRLLLR PRAPVRLLSA 480
ELGPRLPPLL DDTRDSIRAS AVGLLGTLVR RGRGGLRLGL RGPLRKLVLQ SLVPLLLRLH 540
DPSRDAAESS EWTLARCDHA FCWGLLEELV TVAHYDSPEA LSHLCCRLVQ RYPGHVPNFL 600
SQTQGYLRSP QDPLRRAAAV LIGFLVHHAS PGCVNQDLLD SLFQDLGRLQ SDPKPAVAAA 660
AHVSAQQVAM LARARGCPRG PRLLRIAPRP ARPPPVFADS PFQRRSVAGR WGCSGPRRA 719 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold. 
Pfam
  
SMART
  
PROSITE
 PS50077; HEAT_REPEAT 
PRINTS