CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019542
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Perilipin-4 
Protein Synonyms/Alias
 Adipocyte protein S3-12 
Gene Name
 PLIN4 
Gene Synonyms/Alias
 KIAA1881 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
71KELQPSEKQMVSGAKubiquitination[1]
78KQMVSGAKDLVCSKMubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 May play a role in triacylglycerol packaging into adipocytes. May function as a coat protein involved in the biogenesis of lipid droplets (By similarity). 
Sequence Annotation
 REPEAT 95 127 1.
 REPEAT 128 160 2.
 REPEAT 161 193 3.
 REPEAT 194 226 4.
 REPEAT 227 259 5.
 REPEAT 260 292 6.
 REPEAT 293 325 7.
 REPEAT 326 358 8.
 REPEAT 359 391 9.
 REPEAT 392 424 10.
 REPEAT 425 457 11.
 REPEAT 458 490 12.
 REPEAT 491 523 13.
 REPEAT 524 556 14.
 REPEAT 557 589 15.
 REPEAT 590 622 16.
 REPEAT 623 655 17.
 REPEAT 656 688 18.
 REPEAT 689 721 19.
 REPEAT 722 754 20.
 REPEAT 755 787 21.
 REPEAT 788 820 22.
 REPEAT 821 853 23.
 REPEAT 854 886 24.
 REPEAT 887 919 25.
 REPEAT 920 952 26.
 REPEAT 953 985 27.
 REGION 95 985 27 X 33 AA approximate tandem repeat.  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Cytoplasm; Lipid droplet; Membrane; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1357 AA 
Protein Sequence
MQTLGSFFGS LPGFSSARNL VANAHSSARA RPAADPTGAP AAEAAQPQAQ VAAHPEQTAP 60
WTEKELQPSE KQMVSGAKDL VCSKMSRAKD AVSSGVASVV DVAKGVVQGG LDTTRSALTG 120
TKEVVSSGVT GAMDMAKGAV QGGLDTSKAV LTGTKDTVST GLTGAVNVAK GTVQAGVDTT 180
KTVLTGTKDT VTTGVMGAVN LAKGTVQTGV ETSKAVLTGT KDAVSTGLTG AVNVARGSIQ 240
TGVDTSKTVL TGTKDTVCSG VTGAMNVAKG TIQTGVDTSK TVLTGTKDTV CSGVTGAMNV 300
AKGTIQTGVD TSKTVLTGTK DTVCSGVTGA MNVAKGTIQT GVDTTKTVLT GTKNTVCSGV 360
TGAVNLAKEA IQGGLDTTKS MVMGTKDTMS TGLTGAANVA KGAMQTGLNT TQNIATGTKD 420
TVCSGVTGAM NLARGTIQTG VDTTKIVLTG TKDTVCSGVT GAANVAKGAV QGGLDTTKSV 480
LTGTKDAVST GLTGAVNVAK GTVQTGVDTT KTVLTGTKDT VCSGVTSAVN VAKGAVQGGL 540
DTTKSVVIGT KDTMSTGLTG AANVAKGAVQ TGVDTAKTVL TGTKDTVTTG LVGAVNVAKG 600
TVQTGMDTTK TVLTGTKDTI YSGVTSAVNV AKGAVQTGLK TTQNIATGTK NTFGSGVTSA 660
VNVAKGAAQT GVDTAKTVLT GTKDTVTTGL MGAVNVAKGT VQTSVDTTKT VLTGTKDTVC 720
SGVTGAANVA KGAIQGGLDT TKSVLTGTKD AVSTGLTGAV KLAKGTVQTG MDTTKTVLTG 780
TKDAVCSGVT GAANVAKGAV QMGVDTAKTV LTGTKDTVCS GVTGAANVAK GAVQTGLKTT 840
QNIATGTKNT LGSGVTGAAK VAKGAVQGGL DTTKSVLTGT KDAVSTGLTG AVNLAKGTVQ 900
TGVDTSKTVL TGTKDTVCSG VTGAVNVAKG TVQTGVDTAK TVLSGAKDAV TTGVTGAVNV 960
AKGTVQTGVD ASKAVLMGTK DTVFSGVTGA MSMAKGAVQG GLDTTKTVLT GTKDAVSAGL 1020
MGSGNVATGA THTGLSTFQN WLPSTPATSW GGLTSSRTTD NGGEQTALSP QEAPFSGIST 1080
PPDVLSVGPE PAWEAAATTK GLATDVATFT QGAAPGREDT GLLATTHGPE EAPRLAMLQN 1140
ELEGLGDIFH PMNAEEQAQL AASQPGPKVL SAEQGSYFVR LGDLGPSFRQ RAFEHAVSHL 1200
QHGQFQARDT LAQLQDCFRL IEKAQQAPEG QPRLDQGSGA SAEDAAVQEE RDAGVLSRVC 1260
GLLRQLHTAY SGLVSSLQGL PAELQQPVGR ARHSLCELYG IVASAGSVEE LPAERLVQSR 1320
EGVHQAWQGL EQLLEGLQHN PPLSWLVGPF ALPAGGQ 1357 
Gene Ontology
 GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. 
Interpro
 IPR004279; Perilipin. 
Pfam
 PF03036; Perilipin 
SMART
  
PROSITE
  
PRINTS