CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014255
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Growth arrest-specific protein 8 
Protein Synonyms/Alias
 GAS-8; Growth arrest-specific protein 11; GAS-11 
Gene Name
 Gas8 
Gene Synonyms/Alias
 Gas11 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
285RLADPLQKAKDEMNEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility. 
Sequence Annotation
 REGION 1 114 Regulates microtubule-binding.
 REGION 115 258 Microtubule-binding.  
Keyword
 Cell projection; Cilium; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Flagellum; Golgi apparatus; Microtubule; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 478 AA 
Protein Sequence
MAPKKKGKKG KAKGTAIVDG VAPEDMTKEQ VEEHVARIRE ELDREREERN YFQLERDKIH 60
TFWEITRRQL EEKKAELRNK DREMEEAEER HQVEIKVYKQ KVKHLLYEHQ NNLAEVKAEG 120
TVVMKLAQKE HRTQEGALRK DMRVLKVELK EQELANEVVI KNLCLKQAEE ITKMRNDFER 180
QVREIEAKYD KKMKMLRDEL DLRRKTEIHE VEERKNGQIS TLMQRHEEAF TDIKNYYNDI 240
TLNNLALINS LKEQMEDMRK KEEHMEREMA EVTLQNRRLA DPLQKAKDEM NEMQKRLGNH 300
ERDKQILVCT KARLKVAERE LKDLKWEHEV LEQRFIKVQQ EREELYRKFA DAIQEVQQKT 360
GFKNLLLERK LQALNAAVEK REVQFNEVLA ASNLDPTALT LVSRKLEDVL ESKNTTIKDL 420
QYELARVCKA HNDLLRTYEA KLLAFGIPLD NVGFKPLETA VIGQTLGQGP AGLVGAPT 478 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:MGI.
 GO:0005874; C:microtubule; IDA:UniProtKB.
 GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.
 GO:0031514; C:motile cilium; IDA:MGI.
 GO:0017137; F:Rab GTPase binding; IDA:MGI.
 GO:0034613; P:cellular protein localization; IDA:MGI.
 GO:0030317; P:sperm motility; IEP:UniProtKB. 
Interpro
 IPR025593; GAS8. 
Pfam
 PF13851; GAS 
SMART
  
PROSITE
  
PRINTS