CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031656
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Echinoderm microtubule-associated protein-like 4 
Protein Synonyms/Alias
  
Gene Name
 EML4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
573IRAVAEGKADQFLVGubiquitination[1]
878IQWKLVEKLSLPQNEubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 992 AA 
Protein Sequence
MDGFAGSLDD SISAASTSDV QDRLSALESR VQQQEDEITV LKAALADVLR RLAISEDHVA 60
SVKKSVSSKG QPSPRAVIPM SCITNGSGAN RKPSHTSAVS IAGKETLSSA AKSGTEKKKE 120
KPQGQREKKE ESHSNDQSPQ IRASPSPQPS SQPLQIHRQT PESKNATPTK SIKRPSPAEK 180
SHNSWENSDD SRNKLSKIPS TPKLIPKVTK TADKHKDVII NQAKMSTREK NSQEGEYIKM 240
FMRGRPITMF IPSDVDNYDD IRTELPPEKL KLEWAYGYRG KDCRANVYLL PTGKIVYFIA 300
SVVVLFNYEE RTQRHYLGHT DCVKCLAIHP DKIRIATGQI AGVDKDGRPL QPHVRVWDSV 360
TLSTLQIIGL GTFERGVGCL DFSKADSGVH LCIIDDSNEH MLTVWDWQKK AKGAEIKTTN 420
EVVLAVEFHP TDANTIITCG KSHIFFWTWS GNSLTRKQGI FGKYEKPKFV QCLAFLGNGD 480
VLTGDSGGVM LIWSKTTVEP TPGKGPKGVY QISKQIKAHD GSVFTLCQMR NGMLLTGGGK 540
DRKIILWDHD LNPEREIEVP DQYGTIRAVA EGKADQFLVG TSRNFILRGT FNDGFQIEVQ 600
GHTDELWGLA THPFKDLLLT CAQDRQVCLW NSMEHRLEWT RLVDEPGHCA DFHPSGTVVA 660
IGTHSGRWFV LDAETRDLVS IHTDGNEQLS VMRYSIDGTF LAVGSHDNFI YLYVVSENGR 720
KYSRYGRCTG HSSYITHLDW SPDNKYIMSN SGDYEILYWD IPNGCKLIRN RSDCKDIDWT 780
TYTCVLGFQV FGVWPEGSDG TDINALVRSH NRKVIAVADD FCKVHLFQYP CSKAKAPSHK 840
YSAHSSHVTN VSFTHNDSHL ISTGGKDMSI IQWKLVEKLS LPQNETVADT TLTKAPVSST 900
ESVIQSNTPT PPPSQPLNET AEEESRISSS PTLLENSLEQ TVEPSEDHSE EESEEGSGDL 960
GEPLYEEPCN EISKEQAKAT LLEDQQDPSP SS 992 
Gene Ontology
  
Interpro
 IPR005108; HELP.
 IPR011047; Quinonprotein_ADH-like_supfam.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF03451; HELP
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS