UniProt Accession

 SPIN1_MOUSE; Q61142; Q3TLC3; Q3UT05; Q91VG8 

Genbank Protein ID

 U48972; AK088127; AK134259; AK136251; AK139899; AK162171; AK162195; AK162258; AK163263; AK163293; AK163382; AK166528; AK166580; AK166677; AK168544; BC016517 

Genbank Nucleotide ID

 AAA91233.1; BAC40162.1; BAE22069.1; BAE22897.1; BAE24175.1; BAE36769.1; BAE36784.1; BAE36820.1; BAE37266.1; BAE37280.1; BAE37327.1; BAE38832.1; BAE38869.1; BAE38937.1; BAE40420.1; AAH16517.1 

Protein Name

 Spindlin-1 

Protein Synonyms/Alias

 30000 Mr metaphase complex; SSEC P 

Gene Name

 Spin1 

Gene Synonyms/Alias

 Spin 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
44	RTSVGPSKPVSQPRR	acetylation	[1]
44	RTSVGPSKPVSQPRR	ubiquitination	[2]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 May play a role in cell-cycle regulation during the transition from gamete to embryo. 

Sequence Annotation

 REGION 53 116 Tudor-like domain 1 (By similarity).
 REGION 132 193 Tudor-like domain 2 (By similarity).
 REGION 213 262 Tudor-like domain 3 (By similarity).
 MOD_RES 124 124 Phosphoserine (By similarity).
 MOD_RES 199 199 Phosphoserine (By similarity).  

Keyword

 Alternative splicing; Cell cycle; Complete proteome; Cytoplasm; Cytoskeleton; Developmental protein; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 262 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005819; C:spindle; IDA:MGI.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0007143; P:female meiosis; IC:MGI.
 GO:0007276; P:gamete generation; IEA:InterPro.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. 

Interpro

 IPR003671; Spin_Ssty. 

Pfam

 PF02513; Spin-Ssty 

SMART

  

PROSITE

  

PRINTS