UniProt Accession

 B7Z4R0_HUMAN; B7Z4R0 

Genbank Protein ID

 AC006486; AK297666; CH471126 

Genbank Nucleotide ID

 BAH12646.1; EAW57118.1 

Protein Name

 ETS domain-containing transcription factor ERF 

Protein Synonyms/Alias

 Ets2 repressor factor, isoform CRA_b; cDNA FLJ51249, highly similar to ETS domain-containing transcription factor ERF 

Gene Name

 ERF 

Gene Synonyms/Alias

 hCG_20354 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
30	KGKRFTYKFNFNKLV	ubiquitination	[1, 2, 3]
319	RQRAAGEKAVAGADK	acetylation	[3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 473 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:Compara.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0060710; P:chorio-allantoic fusion; IEA:Compara.
 GO:0010668; P:ectodermal cell differentiation; IEA:Compara.
 GO:0060707; P:trophoblast giant cell differentiation; IEA:Compara. 

Interpro

 IPR000418; Ets_dom.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00178; Ets 

SMART

 SM00413; ETS 

PROSITE

 PS50061; ETS_DOMAIN_3 

PRINTS