CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015933
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 KDEL motif-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 KDELC2 
Gene Synonyms/Alias
 UNQ1904/PRO4350 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
307TGPSWINKTERAFFRubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
 REPEAT 24 134 Filamin.
 MOTIF 504 507 Prevents secretion from ER (Potential).
 CARBOHYD 61 61 N-linked (GlcNAc...).
 CARBOHYD 306 306 N-linked (GlcNAc...).  
Keyword
 Alternative splicing; Complete proteome; Endoplasmic reticulum; Glycoprotein; Polymorphism; Reference proteome; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 507 AA 
Protein Sequence
MRRLPRALLL QLRLALLVAA GAPEVLVSAP RSLVWGPGLQ AAVVLPVRYF YLQAVNSEGQ 60
NLTRSPAGET PFKVVVKSLS PKELVRIHVP KPLDRNDGTF LMRYRMYETV DEGLKIEVLY 120
GDEHVAQSPY ILKGPVYHEY CECPEDPQAW QKTLSCPTKE PQIAKDFASF PSINLQQMLK 180
EVPKRFGDER GAIVHYTILN NHVYRRSLGK YTDFKMFSDE ILLSLTRKVL LPDLEFYVNL 240
GDWPLEHRKV NGTPSPIPII SWCGSLDSRD VVLPTYDITH SMLEAMRGVT NDLLSIQGNT 300
GPSWINKTER AFFRGRDSRE ERLQLVQLSK ENPQLLDAGI TGYFFFQEKE KELGKAKLMG 360
FFDFFKYKYQ VNVDGTVAAY RYPYLMLGDS LVLKQDSPYY EHFYMALEPW KHYVPIKRNL 420
SDLLEKVKWA KENDEEAKKI AKEGQLMARD LLQPHRLYCY YYQVLQKYAE RQSSKPEVRD 480
GMELVPQPED STAICQCHRK KPSREEL 507 
Gene Ontology
 GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell. 
Interpro
 IPR001298; Filamin.
 IPR017868; Filamin/ABP280_repeat-like.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR006598; LipoPS_modifying. 
Pfam
 PF00630; Filamin
 PF05686; Glyco_transf_90 
SMART
 SM00672; CAP10
 SM00557; IG_FLMN 
PROSITE
 PS00014; ER_TARGET
 PS50194; FILAMIN_REPEAT 
PRINTS