UniProt Accession

 SEC22_YEAST; P22214; D6VYR6 

Genbank Protein ID

 X54236; U17244; AY557935; BK006945 

Genbank Nucleotide ID

 CAA38142.1; AAB67373.1; AAS56261.1; DAA09582.1 

Protein Name

 Protein transport protein SEC22 

Protein Synonyms/Alias

 Suppressor of loss of YPT1 protein 2 

Gene Name

 SEC22 

Gene Synonyms/Alias

 SLY2; TSL26; YLR268W; L8479.3 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
144	NQELVGVKQIMSKNI	ubiquitination	[1]
172	SDMSSSLKETSKRYR	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Nonessential SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. 

Sequence Annotation

 DOMAIN 6 117 Longin.
 DOMAIN 132 192 v-SNARE coiled-coil homology.
 MOD_RES 160 160 Phosphoserine.  

Keyword

 Coiled coil; Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 214 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IDA:SGD.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0012507; C:ER to Golgi transport vesicle membrane; IDA:SGD.
 GO:0005794; C:Golgi apparatus; IDA:SGD.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IDA:SGD.
 GO:0031201; C:SNARE complex; IDA:SGD.
 GO:0005484; F:SNAP receptor activity; IDA:SGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.
 GO:0048279; P:vesicle fusion with endoplasmic reticulum; IC:SGD.
 GO:0048280; P:vesicle fusion with Golgi apparatus; IMP:SGD. 

Interpro

 IPR011012; Longin-like_dom.
 IPR010908; Longin_dom.
 IPR001388; Synaptobrevin. 

Pfam

 PF13774; Longin
 PF00957; Synaptobrevin 

SMART

  

PROSITE

 PS50859; LONGIN
 PS00417; SYNAPTOBREVIN
 PS50892; V_SNARE 

PRINTS