CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017226
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-binding cassette sub-family F member 3 
Protein Synonyms/Alias
  
Gene Name
 Abcf3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
294QLAEIYGKLEEIEADubiquitination[1]
302LEEIEADKAPARASVubiquitination[1]
616ASLSGGQKSRVAFAQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B. 
Sequence Annotation
 DOMAIN 178 424 ABC transporter 1.
 DOMAIN 492 707 ABC transporter 2.
 NP_BIND 210 217 ATP 1 (Potential).
 NP_BIND 525 532 ATP 2 (Potential).
 MOD_RES 283 283 Phosphoserine (By similarity).  
Keyword
 Antiviral defense; ATP-binding; Complete proteome; Nucleotide-binding; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 709 AA 
Protein Sequence
MATCADILRS EFPEIDGQVF DYVTGVLHSG SADFESVDDL VEAVGELLQE VSGDSKDDAG 60
IRAVCQRMYN TLRLAEPQNQ GNSQVLLDAP IQLSKIMENY DCDTKLPGLL KREQSSTVNA 120
KKLEKAEARL KAKQEKRSEK ETLKTSNPLV LEEASASQAG SRKESRLESS GKNKSYDVRI 180
ENFDVSFGDR VLLAGADVNL AWGRRYGLVG RNGLGKTTLL KMLATRSLRV PAHISLLHVE 240
QEVAGDDTPA LQSVLESDTV REDLLRQERE LSLRIAAGRA EGSEAAQLAE IYGKLEEIEA 300
DKAPARASVI LAGLGFTPKM QQQPTREFSG GWRMRLALAR ALFARPDLLL LDEPTNMLDV 360
RAILWLENYL QTWPSTILVV SHDRNFLNAI ATDIIHLHSQ RLDGYRGDFE TFIKSKQERL 420
LNQQREYEAQ QQYRQHIQVF IDRFRYNANR ASQVQSKLKM LEKLPELKPV DKESEVVLKF 480
PDGFEKFSPP ILQLDEVDFY YDPKHSIFSR LSVSADLESR ICVVGENGAG KSTMLKLLMG 540
DLSPVRGIRH AHRNLKIGYF SQHHVEQLDL NVSAVELLAR KFPGLPEEEY RHQLGRYGIS 600
GELAMRPVAS LSGGQKSRVA FAQMTMPCPN FYILDEPTNH LDMETIEALG QALNNFRGGV 660
ILVSHDERFI RLVCKELWVC ENGSVTRVEG GFDQYRALLQ EQFRREGFL 709 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0051607; P:defense response to virus; IEA:UniProtKB-KW. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS