CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043743
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Insulin-like peptide INSL6 
Protein Synonyms/Alias
  
Gene Name
 RIF1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
243KNETYVLKLWPLFVKubiquitination[1]
511VTESGNKKEKPGSEVmethylation[2]
513ESGNKKEKPGSEVLTmethylation[2]
694RFPVATMKTLLRTWSubiquitination[1, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 845 AA 
Protein Sequence
XAGKVELWQR LGAEGQRRRE PCPDLPSRMT GEEGKEVITE IEKKLPRLYK VLKTHISSQN 60
SELSSAALQA LGFCLYNPKI TSELSEANAL ELLSKLNDTI KNSDKNVRTR ALWVISKQTF 120
PSEVVGKMVS SIIDSLEILF NKGETHSAVV DFEALNVIVR LIEQAPIQMG EEAVRWAKLV 180
IPLVVHSAQK VHLRGATALE MGMPLLLQKQ QEIASITEQL MTTKLISELQ KLFMSKNETY 240
VLKLWPLFVK LLGRTLHRSG SFINSLLQLE ELGFRSGAPM IKKIAFIAWK SLIDNFALNP 300
DILCSAKRLK LLMQPLSSIH VRTETLALTK LEVWWYLLMR LGPHLPANFE QVCVPLIQST 360
ISIDSNASPQ GNSCHVATSP GLNPMTPVHK GASSPYGAPG TPRMNLSSNL GGMATIPSIQ 420
LLGLEMLLHF LLGPEALSFA KQNKLVLSLE PLEHPLISSP SFFSKHANTL ITAVHDSFVA 480
VGKDAPDVVV SAIWKELISL VKSVTESGNK KEKPGSEVLT LLLKSLESIV KSEVFPVSKT 540
LVLMEITIKG LPQKVLGSPA YQVANMDILN GTPALFLIQL IFNNFLECGV SDERFFLSLE 600
SLVGCVLSGP TSPLAFSDSV LNVINQNAKQ LENKEHLWKM WSVIVTPLTE LINQTNEVNQ 660
GDALEHNFSA IYGALTLPVN HIFSEQRFPV ATMKTLLRTW SELYRAFARC AALVATAEEN 720
LCCEELSSKI MSSLEDEGFS NLLFVDRIIY IITVMVDCID FSPYNIKYQP KVKSPQRPSD 780
WSKKKNEPLG KLTSLFKLIV KVIYSFHTLS FKEAHSDTLF TIGNSITGII SSVLGHISLP 840
SMIRK 845 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR022031; Rif1_N. 
Pfam
 PF12231; Rif1_N 
SMART
  
PROSITE
  
PRINTS