UniProt Accession

 GSF2_YEAST; Q04697; D6VZC7 

Genbank Protein ID

 Z47816; AY692925; BK006946 

Genbank Nucleotide ID

 CAA87826.1; AAT92944.1; DAA09851.1 

Protein Name

 Glucose-signaling factor 2 

Protein Synonyms/Alias

 Extracellular mutant protein 6 

Gene Name

 GSF2 

Gene Synonyms/Alias

 ECM6; EFF2; YML048W; YM9827.04 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
240	NNNTTDLKTRLRSLG	acetylation	[1]
337	ELENNLKKILEEYDG	ubiquitination	[2]
367	GIYEPDEKLASLVKL	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 May be involved in the secretion of hexose transporters from the endoplasmic reticulum. Involved in secretion of GAL2 and HXT1. 

Sequence Annotation

 CARBOHYD 89 89 N-linked (GlcNAc...) (Potential).
 CARBOHYD 173 173 N-linked (GlcNAc...) (Potential).  

Keyword

 Coiled coil; Complete proteome; Endoplasmic reticulum; Glycoprotein; Membrane; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 403 AA 

Protein Sequence

Gene Ontology

 GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.
 GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
 GO:0051082; F:unfolded protein binding; IMP:SGD.
 GO:0006457; P:protein folding; IMP:SGD.
 GO:0034394; P:protein localization to cell surface; IMP:SGD. 

Interpro

 IPR022757; Gsf2. 

Pfam

 PF11055; Gsf2 

SMART

  

PROSITE

  

PRINTS