CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041369
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Acylphosphatase 
Protein Synonyms/Alias
  
Gene Name
 ACYP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
63HTQAEGKKLGLVGWVubiquitination[1]
88QLQGPISKVRHMQEWubiquitination[1, 2, 3]
119NNEKVILKLDYSDFQubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 129 AA 
Protein Sequence
MPASARLAGA GLLLAFLRAL GCAGRAPGLS MAEGNTLISV DYEIFGKVQG VFFRKHTQAE 60
GKKLGLVGWV QNTDRGTVQG QLQGPISKVR HMQEWLETRG SPKSHIDKAN FNNEKVILKL 120
DYSDFQIVK 129 
Gene Ontology
 GO:0003998; F:acylphosphatase activity; IEA:EC. 
Interpro
 IPR020456; Acylphosphatase.
 IPR001792; Acylphosphatase-like.
 IPR017968; Acylphosphatase_CS. 
Pfam
 PF00708; Acylphosphatase 
SMART
  
PROSITE
 PS00150; ACYLPHOSPHATASE_1
 PS00151; ACYLPHOSPHATASE_2
 PS51160; ACYLPHOSPHATASE_3 
PRINTS
 PR00112; ACYLPHPHTASE.