| Tag | Content |
|---|
| CPLM ID | CPLM-023352 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Methylthioribose-1-phosphate isomerase |
Protein Synonyms/Alias | M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein |
Gene Name | CG11334 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 244 | VAALLRAKNVAAVVV | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity). |
Sequence Annotation | ACT_SITE 254 254 Proton donor (By similarity). |
Keyword | Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase; Methionine biosynthesis; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 364 AA |
Protein Sequence | MSLQSIKYSR GSLEILDQLL LPGQSKYVVV RGVEDGWKVI NKMQVRGAPA IAIVGCLSLA 60
VEINPEDFEN KKSLRQEIEG KLNYLVSARP TAVNMKIAAD ELITLANELY KDEAIDVTQM 120
KHRFLDATEA MLKKDIADNR AIGANGAQAI LQGVAKAGKA PAGSTGSVRV LTHCNTGSLA 180
TAGYGTALGV VRQLAELGKL EHVYCTETRP YNQGARLTAY ELVHEKFPAT LVLDSMVAAL 240
LRAKNVAAVV VGADRVASNG DTANKIGTYQ IAVVAKHHDV PFYVAAPLTS IDLAIPGGDH 300
IIIEERPDRE MTHVGEHRIA APGINCWNPA FDVTPASLIT GIITERGVFK PAELKEAITK 360
LLES 364 |
Gene Ontology | GO:0005737; C:cytoplasm; IBA:RefGenome. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IBA:RefGenome. GO:0019284; P:L-methionine biosynthetic process from S-adenosylmethionine; IEA:HAMAP. GO:0019509; P:L-methionine salvage from methylthioadenosine; IBA:RefGenome. GO:0035220; P:wing disc development; IGI:FlyBase. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |