CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037988
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 
Protein Synonyms/Alias
  
Gene Name
 Atp2a2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
130EYEPEMGKVYRQDRKacetylation[1]
171DIRLTSIKSTTLRVDacetylation[1]
191GESVSVIKHTDPVPDacetylation[1]
206PRAVNQDKKNMLFSGacetylation[1]
207RAVNQDKKNMLFSGTacetylation[1]
462NVFDTELKGLSKIERacetylation[1]
466TELKGLSKIERANACacetylation[1]
512PSRTSMSKMFVKGAPacetylation[1]
516SMSKMFVKGAPEGVIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Membrane; Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 999 AA 
Protein Sequence
MENAHTKTVE EVLGHFGVNE STGLSLEQVK KLKERWGSNE LPAEEEKDIN QLFLLLHFAL 60
FLRTRVFIFY NNFHNVLAWF EEGEETITAF VEPFVILLIL VANAIVGVWQ ERNAENAIEA 120
LKEYEPEMGK VYRQDRKSVQ RIKAKDIVPG DIVEIAVGDK VPADIRLTSI KSTTLRVDQS 180
ILTGESVSVI KHTDPVPDPR AVNQDKKNML FSGTNIAAGK AMGVVVATGV NTEIGKIRDE 240
MVATEQERTP LQQKLDEFGE QLSKVISLIC IAVWIINIGH FNDPVHGGSW IRGAIYYFKI 300
AVALAVAAIP EGLPAVITTC LALGTRRMAK KNAIVRSLPS VETLGCTSVI CSDKTGTLTT 360
NQMSVCRMFI LDKVEGDTCS LNEFTITGST YAPIGEVQKD DKPVKCHQYD GLVELATICA 420
LCNDSALDYN EAKGVYEKVG EATETALTCL VEKMNVFDTE LKGLSKIERA NACNSVIKQL 480
MKKEFTLEFS RDRKSMSVYC TPNKPSRTSM SKMFVKGAPE GVIDRCTHIR VGSTKVPMTP 540
GVKQKIMSVI REWGSGSDTL RCLALATHDN PLRREEMHLE DSANFIKYET NLTFVGCVGM 600
LDPPRIEVAS SVKLCRQAGI RVIMITGDNK GTAVAICRRI GIFGQDEDVT SKAFTGREFD 660
ELSPSAQRDA CLNARCFARV EPSHKSKIVE FLQSFDEITA MTGDGVNDAP ALKKSEIGIA 720
MGSGTAVAKT ASEMVLADDN FSTIVAAVEE GRAIYNNMKQ FIRYLISSNV GEVVCIFLTA 780
ALGFPEALIP VQLLWVNLVT DGLPATALGF NPPDLDIMNK PPRNPKEPLI SGWLFFRYLA 840
IGCYVGAATV GAAAWWFIAA DGGPRVSFYQ LSHFLQCKED NPDFEGVDCA IFESPYPMTM 900
ALSVLVTIEM CNALNSLSEN QSLLRMPPWE NIWLVGSICL SMSLHFLILY VEPLPLIFQI 960
TPLNLTQWLM VLKISLPVIL MDETLKFVAR NYLEPAILE 999 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005388; F:calcium-transporting ATPase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro. 
Interpro
 IPR005782; ATPase_P-typ_Ca-transp_IIA.
 IPR006068; ATPase_P-typ_cation-transptr_C.
 IPR004014; ATPase_P-typ_cation-transptr_N.
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR023298; ATPase_P-typ_TM_dom.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00689; Cation_ATPase_C
 PF00690; Cation_ATPase_N
 PF00122; E1-E2_ATPase
 PF00702; Hydrolase 
SMART
 SM00831; Cation_ATPase_N 
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS
 PR00119; CATATPASE.
 PR00120; HATPASE.