UniProt Accession

 EMC10_HUMAN; Q5UCC4; Q5UCC6; Q69YT5; Q6UWP3; Q86YL4; Q8N541 

Genbank Protein ID

 AY194293; AY761095; AY761097; CH471135; BC032948; BC035001; AY358710; AL512761 

Genbank Nucleotide ID

 AAO23975.2; AAV30543.1; AAV30545.1; EAW71871.1; AAH32948.1; AAH35001.1; AAQ89073.1; CAH10658.1 

Protein Name

 ER membrane protein complex subunit 10 

Protein Synonyms/Alias

 Hematopoietic signal peptide-containing membrane domain-containing protein 1 

Gene Name

 EMC10 

Gene Synonyms/Alias

 C19orf63; HSM1; INM02; UNQ764/PRO1556 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
212	LEMEQAQKAKNPQEQ	ubiquitination	[1, 2]
214	MEQAQKAKNPQEQKS	ubiquitination	[1, 2]
220	AKNPQEQKSFFAKYW	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

 CARBOHYD 182 182 N-linked (GlcNAc...).  

Keyword

 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Reference proteome; Secreted; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 262 AA 

Protein Sequence

Gene Ontology

 GO:0072546; C:ER membrane protein complex; IDA:UniProtKB.
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS