| Tag | Content |
|---|
| CPLM ID | CPLM-017886 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | TBC1 domain family member 22A |
Protein Synonyms/Alias | |
Gene Name | Tbc1d22a |
Gene Synonyms/Alias | D15Ertd781e |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 216 | TDLEELRKLSWSGIP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May act as a GTPase-activating protein for Rab family protein(s) (By similarity). |
Sequence Annotation | DOMAIN 221 445 Rab-GAP TBC. |
Keyword | Alternative splicing; Complete proteome; GTPase activation; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 516 AA |
Protein Sequence | MASDGARKQF WKRSNSKVPG SIQHVYGAQH PPFDPLLHGT LLKSTPKVPT TPVKAKRVST 60
FQEFESNTSD AWDAGEDDDE LLAMATESLN SEVVMETAHR VLRNHSQRQS QPSQKTTEPE 120
PEPQPIAEPP VPPSGDLRLV KSVSESHTPC PSESTGDTVP LQRSQSLPHS ATVTLSGTSD 180
PHALADSALS KRETSRLDKF KQLLAGPNTD LEELRKLSWS GIPKPVRPMT WKLLSGYLPA 240
NVDRRPATLQ RKQKEYFAFI EHYYSSRNDE VHQDTYRQIH IDIPRMSPEA LILQPKVTEI 300
FERILFIWAI RHPASGYVQG INDLVTPFFV VFICEYTDRE DVDKVDVSSV PAEVLRNIEA 360
DTYWCMSKLL DGIQDNYTFA QPGIQMKVKM LEELVSRIDE RVHRHLDGHE VRYLQFAFRW 420
MNNLLMRELP LRCTIRLWDT YQSEPEGFSH FHLYVCAAFL VRWRREILEE RDFQELLLFL 480
QNLPTARWDD QDVSLLLAEA YRLKFAFADA PNHYKK 516 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |