CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029165
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger protein 419 
Protein Synonyms/Alias
  
Gene Name
 ZNF419 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
154LQSREVGKALLISSGubiquitination[1]
203CGKAFGQKYLLVQHQubiquitination[1]
320SFNSSLMKHQRIHTGubiquitination[1]
422YECRECGKFFRHNSSubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 442 AA 
Protein Sequence
MAAAALRDPA QQGYVTFEDV AVYFSQEEWR LLDDAQRLLY RNVMLENFTL LASLGLASSK 60
THEITQLESW EEPFMPAWEV VTSAIPRGCW HGAEAEEAPE QIASVGLLSS NIQQHQKQHC 120
GEKPLKRQEG RVPVLRSCKV HLSEKSLQSR EVGKALLISS GVLKHQVTHT GEKSHRSSKS 180
REAFHAGKRH YKCSECGKAF GQKYLLVQHQ RLHAGKKTYE CSECGKLFRD MSNLFIHQIV 240
HTGERPYGCS NCGKSFSRNA HLIEHQRVHT GEKPFTCSEC GKAFRHNSTL VQHHKIHTGV 300
RPYECSECGK LFSFNSSLMK HQRIHTGERP YKCSECGKFY SHKSNLIKHW RVHTGERPYK 360
CSDCGKFFTQ CSSLMQHQKV HTGEKPFKCN ECGRFFRENS SLVKHQRVHT GAKPYECREC 420
GKFFRHNSSL FKHRRIHTGE MQ 442 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS