CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015054
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 3-isopropylmalate dehydratase small subunit 
Protein Synonyms/Alias
 Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase 
Gene Name
 leuD 
Gene Synonyms/Alias
 RPA0235 
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
3*****MDKFTTLEGVacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131
Functional Description
 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity). 
Sequence Annotation
  
Keyword
 Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; Leucine biosynthesis; Lyase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 201 AA 
Protein Sequence
MDKFTTLEGV AAPLKIINVD TDMIIPKQYL KTIKRTGLGK GLFSEQRYKD DGSENPDFIL 60
NKPAYRGAKI LVAGDNFGCG SSREHAPWAL LDFGIRCVIS TSFGDIFYNN CFKNGVLPIR 120
VSQADLDKLF DDAERGSNAT MTIDLQAQEI RGPDGGAIKF EIDPFRKHCL INGLDDIGLT 180
LEKKPSIDAY ETKLKTERAW A 201 
Gene Ontology
 GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
 GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:HAMAP.
 GO:0009098; P:leucine biosynthetic process; IEA:HAMAP. 
Interpro
 IPR004431; 3-IsopropMal_deHydase_ssu.
 IPR015937; Acoase/IPM_deHydtase.
 IPR015928; Aconitase/3IPM_dehydase_swvl.
 IPR000573; AconitaseA/IPMdHydase_ssu_swvl. 
Pfam
 PF00694; Aconitase_C 
SMART
  
PROSITE
  
PRINTS