| Tag | Content |
|---|
| CPLM ID | CPLM-010180 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ribosomal RNA large subunit methyltransferase F |
Protein Synonyms/Alias | 23S rRNA mA1618 methyltransferase; rRNA adenine N-6-methyltransferase |
Gene Name | rlmF |
Gene Synonyms/Alias | ybiN; b0807; JW5107 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 175 | IFNGIIHKNEQYDAT | acetylation | [1] | | 274 | LTDVGAVKVVKKEMA | acetylation | [1] | | 277 | VGAVKVVKKEMAQGQ | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Specifically methylates the adenine in position 1618 of 23S rRNA. |
Sequence Annotation | |
Keyword | Complete proteome; Cytoplasm; Methyltransferase; Reference proteome; rRNA processing; S-adenosyl-L-methionine; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 308 AA |
Protein Sequence | MSAQKPGLHP RNRHHSRYDL ATLCQVNPEL RQFLTLTPAG EQSVDFANPL AVKALNKALL 60
AHFYAVANWD IPDGFLCPPV PGRADYIHHL ADLLAEASGT IPANASILDI GVGANCIYPL 120
IGVHEYGWRF TGSETSSQAL SSAQAIISSN PGLNRAIRLR RQKESGAIFN GIIHKNEQYD 180
ATLCNPPFHD SAAAARAGSE RKRRNLGLNK DDALNFGGQQ QELWCEGGEV TFIKKMIEES 240
KGFAKQVMWF TSLVSRGENL PPLYRALTDV GAVKVVKKEM AQGQKQSRFI AWTFMNDEQR 300
RRFVNRQR 308 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0052907; F:23S rRNA (adenine(1618)-N(6))-methyltransferase activity; IDA:EcoCyc. GO:0070475; P:rRNA base methylation; IMP:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |