UniProt Accession

 B1AT85_MOUSE; B1AT85 

Genbank Protein ID

 AL645851 

Genbank Nucleotide ID

  

Protein Name

 Sphingosine kinase 1 

Protein Synonyms/Alias

  

Gene Name

 Sphk1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
27	LLNPQGGKGKALQLF	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 116 AA 

Protein Sequence

Gene Ontology

 GO:0005516; F:calmodulin binding; ISA:MGI.
 GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
 GO:0003677; F:DNA binding; ISA:MGI.
 GO:0008481; F:sphinganine kinase activity; ISA:MGI.
 GO:0001568; P:blood vessel development; IGI:MGI.
 GO:0007420; P:brain development; IGI:MGI.
 GO:0006954; P:inflammatory response; IMP:MGI.
 GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
 GO:0032651; P:regulation of interleukin-1 beta production; IMP:MGI. 

Interpro

 IPR001206; Diacylglycerol_kinase_cat_dom. 

Pfam

 PF00781; DAGK_cat 

SMART

  

PROSITE

 PS50146; DAGK 

PRINTS