CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031182
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thioredoxin domain-containing protein 15 
Protein Synonyms/Alias
 cDNA FLJ56237, highly similar to Homo sapiens thioredoxin domain containing 15 (TXNDC15), mRNA 
Gene Name
 TXNDC15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
249ILLFQGAKPMARFNHubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 337 AA 
Protein Sequence
MEAGQQRVVE KVAEESGRLW SEEQPAHPLQ VGAVYLGEEE LLHDPMGQDR AAEEANAVLG 60
LDTQGDHMVM LSVIPGEAED KVSSEPSGVT CGAGGAEDSR CNVRESLFSL DGAGAHFPDR 120
EEEYYTEPEV AESDAAPTED SNNTESLKSP KVNCEERNIT GLENFTLKIL NMSQDLMDFL 180
NPNGSDCTLV LFYTPWCRFS ASLAPHFNSL PRAFPALHFL ALDASQHSSL STRFGTVAVP 240
NILLFQGAKP MARFNHTDRT LETLKIFIFN QTGIEAKKNV VVTQADQIGP LPSTLIKSVD 300
WLLVFSLFFL ISFIMYATIR TESIRWLIPG QEQEHVE 337 
Gene Ontology
 GO:0045454; P:cell redox homeostasis; IEA:InterPro. 
Interpro
 IPR012336; Thioredoxin-like_fold.
 IPR013766; Thioredoxin_domain. 
Pfam
 PF00085; Thioredoxin 
SMART
  
PROSITE
 PS51352; THIOREDOXIN_2 
PRINTS