UniProt Accession

 H0Y4Z6_HUMAN; H0Y4Z6 

Genbank Protein ID

 AL121772 

Genbank Nucleotide ID

  

Protein Name

 Phosphorylase 

Protein Synonyms/Alias

  

Gene Name

 PYGB 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
75	YRVSLAEKVIPAADL	ubiquitination	[1, 2]
159	YDHLPELKQAVDQIS	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). 

Sequence Annotation

  

Keyword

 Carbohydrate metabolism; Complete proteome; Glycosyltransferase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 245 AA 

Protein Sequence

Gene Ontology

 GO:0008184; F:glycogen phosphorylase activity; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW. 

Interpro

 IPR000811; Glyco_trans_35. 

Pfam

 PF00343; Phosphorylase 

SMART

  

PROSITE

 PS00102; PHOSPHORYLASE 

PRINTS