UniProt Accession

 H2A4_ARATH; Q9LZ46 

Genbank Protein ID

 AL162971; CP002688; AY085515 

Genbank Nucleotide ID

 CAB85993.1; AED90489.1; AAM62739.1 

Protein Name

 Probable histone H2A.4 

Protein Synonyms/Alias

 HTA12 

Gene Name

 At5g02560; T22P11.150 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Arabidopsis thaliana (Mouse-ear cress) 

NCBI Taxa ID

 3702 

Lysine Modification

Position	Peptide	Type	References
6	**MDSGTKVKKGAAG	acetylation	[1]

Reference

 [1] Distinctive core histone post-translational modification patterns in Arabidopsis thaliana.
 Zhang K, Sridhar VV, Zhu J, Kapoor A, Zhu JK.
 PLoS One. 2007 Nov 21;2(11):e1210. [PMID: 18030344] 

Functional Description

 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. 

Sequence Annotation

 MOTIF 149 152 SPKK motif.  

Keyword

 Alternative splicing; Chromosome; Complete proteome; DNA-binding; Nucleosome core; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 153 AA 

Protein Sequence

Gene Ontology

 GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR009072; Histone-fold.
 IPR007125; Histone_core_D.
 IPR002119; Histone_H2A. 

Pfam

 PF00125; Histone 

SMART

 SM00414; H2A 

PROSITE

 PS00046; HISTONE_H2A 

PRINTS

 PR00620; HISTONEH2A.