| Tag | Content |
|---|
| CPLM ID | CPLM-006998 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative oxidoreductase TDA3 |
Protein Synonyms/Alias | Batten disease protein 3; Topoisomerase I damage affected protein 3 |
Gene Name | TDA3 |
Gene Synonyms/Alias | BTN3; YHR009C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 150 | RPGYISNKFNIGDSN | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Putative oxidoreductase that negatively regulates the retrieval of cargo from late endosomes to the Golgi. Regulates YIF1 and KEX2 localization. Required for fast DNA replication. |
Sequence Annotation | MOD_RES 189 189 Phosphoserine.
MOD_RES 204 204 Phosphoserine.
MOD_RES 306 306 Phosphoserine. |
Keyword | Complete proteome; Cytoplasm; Endosome; Oxidoreductase; Phosphoprotein; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 523 AA |
Protein Sequence | MGEDFMHPPF QTYPSKNSEG KKHIVIVGGG IIGCCTAYYL TQHPSFSPST HHITIIESRR 60
IAGGASGKAG GLLASWAFPH QIVPLSFQLH QELSDEYDGE NNWDYRRLTT VSLEADVREE 120
VIENYERLSK KAYNLNVPPP KKRPGYISNK FNIGDSNSSL SSSGSSLKND SASNEEEGSD 180
IHVSSSVPSL HSLTNERMRS HTNSASDLDS VSPVEQLRET NIHNPLPADL DWIRRELVND 240
WSSLGGTDTT AQLHPYKFTH FILSKAMETG AVDLLLGKVV GLKCDEMDCV HSLKYLPSVV 300
KNRRNSRGHA ENPDIKLGTI FNDENAKPIE INDIQQIVLS MGPWTSKILK DCPISGLRAH 360
SVTIKPSEKT VSPYAILAEL KVNDREFFSP EMYARKDEVY VCGEGDTLVN IPESSDDVEV 420
VSEKCDELYH YVSKLSPTLS KGHLLRKQAC FLPVLNVPTS SGPLIGETNV KDLYIASGHS 480
CWGINNAPAT GKLMAEILLD GEATSAEISS LDPKLYFDAT ILS 523 |
Gene Ontology | GO:0005770; C:late endosome; IDA:SGD. GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. GO:0042147; P:retrograde transport, endosome to Golgi; IMP:SGD. |
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