UniProt Accession

 CR032_HUMAN; Q8TCD1 

Genbank Protein ID

 AB097012; AK291882; BC022357; BC093004 

Genbank Nucleotide ID

 BAC77365.1; BAF84571.1; AAH22357.1; AAH93004.1 

Protein Name

 UPF0729 protein C18orf32 

Protein Synonyms/Alias

 Putative NF-kappa-B-activating protein 200 

Gene Name

 C18orf32 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
38	FVSRIWPKKAIQESN	ubiquitination	[1, 2, 3]
39	VSRIWPKKAIQESND	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 May activate the NF-kappa-B signaling pathway. 

Sequence Annotation

  

Keyword

 Complete proteome; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 76 AA 

Protein Sequence

Gene Ontology

 GO:0004871; F:signal transducer activity; IMP:UniProtKB.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB. 

Interpro

 IPR026776; UPF0729. 

Pfam

  

SMART

  

PROSITE

  

PRINTS