CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004209
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chitin synthase 2 
Protein Synonyms/Alias
 Chitin-UDP acetyl-glucosaminyl transferase 2 
Gene Name
 CHS2 
Gene Synonyms/Alias
 YBR038W; YBR0407 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
102ANLQESPKRAGEAVIubiquitination[1]
174LAEADDEKEKYLTSTubiquitination[1, 2]
232SDLPPPSKKKALLKLubiquitination[1]
245KLDNPIPKGLLDTLPubiquitination[1]
583KWVLKYVKEATGETDubiquitination[1]
813KGSTQESKQLSKAIVubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Essential for septum formation and cell division. CHS2 is required for maintaining normal cell morphology. 
Sequence Annotation
 MOD_RES 40 40 Phosphoserine.
 MOD_RES 82 82 Phosphoserine.
 MOD_RES 86 86 Phosphoserine.
 MOD_RES 100 100 Phosphoserine.
 MOD_RES 133 133 Phosphoserine.
 CARBOHYD 22 22 N-linked (GlcNAc...) (Potential).
 CARBOHYD 197 197 N-linked (GlcNAc...) (Potential).
 CARBOHYD 447 447 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell wall biogenesis/degradation; Complete proteome; Glycoprotein; Glycosyltransferase; Membrane; Phosphoprotein; Reference proteome; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 963 AA 
Protein Sequence
MTRNPFMVEP SNGSPNRRGA SNLSKFYANA NSNSRWANPS EESLEDSYDQ SNVFQGLPAS 60
PSRAALRYSP DRRHRTQFYR DSAHNSPVAP NRYAANLQES PKRAGEAVIH LSEGSNLYPR 120
DNADLPVDPY HLSPQQQPSN NLFGSGRLYS QSSKYTMSTT STTAPSLAEA DDEKEKYLTS 180
TTSYDDQSTI FSADTFNETK FELNHPTRQQ YVRRANSESK RRMVSDLPPP SKKKALLKLD 240
NPIPKGLLDT LPRRNSPEFT EMRYTACTVE PDDFLREGYT LRFAEMNREC QIAICITMYN 300
EDKYSLARTI HSIMKNVAHL CKREKSHVWG PNGWKKVSVI LISDGRAKVN QGSLDYLAAL 360
GVYQEDMAKA SVNGDPVKAH IFELTTQVSI NADLDYVSKD IVPVQLVFCL KEENKKKINS 420
HRWLFNAFCP VLQPTVVTLV DVGTRLNNTA IYRLWKVFDM DSNVAGAAGQ IKTMKGKWGL 480
KLFNPLVASQ NFEYKISNIL DKPLESVFGY ISVLPGALSA YRYRALKNHE DGTGPLRSYF 540
LGETQEGRDH DVFTANMYLA EDRILCWELV AKRDAKWVLK YVKEATGETD VPEDVSEFIS 600
QRRRWLNGAM FAAIYAQLHF YQIWKTKHSV VRKFFLHVEF LYQFIQMLFS WFSIANFVLT 660
FYYLAGSMNL VIKHGEALFI FFKYLIFCDL ASLFIISMGN RPQGAKHLFI TSMVILSICA 720
TYSLICGFVF AFKSLASGTE SHKIFVDIVI SLLSTYGLYF FSSLMYLDPW HMFTSSIQYF 780
LTLPAFTCTL QIFAFCNTHD VSWGTKGSTQ ESKQLSKAIV VQGPDGKQIV ETDWPQEVDK 840
KFLEIKSRLK EPEFEESSGN EKQSKNDYYR DIRTRIVMIW MLSNLILIMS IIQVFTPQDT 900
DNGYLIFILW SVAALAAFRV VGSMAFLFMK YLRIIVSYRN KVEGSGSWEV SKLDLPNVFH 960
KKG 963 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0004100; F:chitin synthase activity; IDA:SGD.
 GO:0000916; P:actomyosin contractile ring contraction; IDA:SGD.
 GO:0006031; P:chitin biosynthetic process; IMP:SGD. 
Interpro
 IPR004834; Chitin_synth.
 IPR013616; Chitin_synth_N. 
Pfam
 PF01644; Chitin_synth_1
 PF08407; Chitin_synth_1N 
SMART
  
PROSITE
  
PRINTS