CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010168
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Transcription termination/antitermination protein NusA 
Protein Synonyms/Alias
  
Gene Name
 nusA 
Gene Synonyms/Alias
 MPN_154; MP677 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
43TALAQTYKKHLNYVNacetylation[1]
118IKGDLISKMVLLFNQacetylation[1]
383PQGIFGIKKRRDKISacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Participates in both transcription termination and antitermination (By similarity). 
Sequence Annotation
 DOMAIN 144 214 S1 motif.
 DOMAIN 319 386 KH.  
Keyword
 Complete proteome; Cytoplasm; Reference proteome; RNA-binding; Transcription; Transcription antitermination; Transcription regulation; Transcription termination. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 540 AA 
Protein Sequence
MNNQSNHFTN PLLQLIKNVA ETKNLAIDDV VLCLKTALAQ TYKKHLNYVN VEVNIDFNKG 60
LMQIEQLFDV VDDNNEDYDD FLEMPLSEAK KLNPNLEVGG VLRKPVSLKD IKGDLISKMV 120
LLFNQKINET AFKTVMSDFI NEVGQVIEAR VEDIDTNKDG GLKGYIVNLE TTKGYMPKRE 180
LSKGEKLDIG KKYLFVIKEI QKQSSMWPIT LSRSDSRLLE FLLNSNTPEI ANGTIEIKKM 240
ERSPGTKSKV AVISKDPVVD PIAAILGPKG ERIRGISEEF NGEIIDIVIW NEDKLKFLVN 300
AVLPAEVVGY NILQDDERDT SIEIVVPANQ IANVFGFKGI NIRLISNLTG WSSVDVYTEK 360
DAAEQGIEFT RVNFQPQGIF GIKKRRDKIS NNPRNNNQQL ASDKVFYTSK ANVVDDEIIV 420
DLAKQAEAKR VKQIKQEATK PELQLQQELN LEATPKVAAP TPTPAPQPTP APTKVEPVPP 480
PVSVTPKPIP KVNKPKPVVK PKSVFSITVE ADDSKTKPEK SSAKTNTPQT KQTFDNFDDL 540 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006353; P:DNA-dependent transcription, termination; IEA:UniProtKB-KW.
 GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW. 
Interpro
 IPR004087; KH_dom.
 IPR015946; KH_dom-like_a/b.
 IPR025249; KH_dom_NusA-like.
 IPR004088; KH_dom_type_1.
 IPR009019; KH_prok-type.
 IPR012340; NA-bd_OB-fold.
 IPR003029; Rbsml_prot_S1_RNA-bd_dom.
 IPR022967; RNA-binding_domain_S1.
 IPR013735; TF_NusA_N.
 IPR010213; Tscrpt_termination_fac_NusA. 
Pfam
 PF13184; KH_5
 PF08529; NusA_N 
SMART
 SM00322; KH
 SM00316; S1 
PROSITE
 PS50084; KH_TYPE_1
 PS50126; S1 
PRINTS