| Tag | Content |
|---|
| CPLM ID | CPLM-017822 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Spartin |
Protein Synonyms/Alias | |
Gene Name | Spg20 |
Gene Synonyms/Alias | Kiaa0610 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 622 | AMVKKTAKQTGHTLL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be implicated in endosomal trafficking, or microtubule dynamics, or both. |
Sequence Annotation | DOMAIN 16 94 MIT.
MOD_RES 1 1 N-acetylmethionine (By similarity).
MOD_RES 474 474 Phosphoserine (By similarity).
CROSSLNK 360 360 Glycyl lysine isopeptide (Lys-Gly) |
Keyword | Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Isopeptide bond; Phosphoprotein; Reference proteome; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 671 AA |
Protein Sequence | MEREPENGEP AEIKIIKEAY EKAFMFVNKG LNTDELGQKE EAKNYYKQGI GHLLRGISIA 60
AAEPGHTGPA WEAARQMQQK MKETLQNVRT RLEILEKGLA TSLRNDLQDV PKLYPEFPPK 120
DACKKSPEQE SVSTAPQRAE VDGSASAACA GPSGAPSALP VPSPSCPAEA PPAYSPQAAE 180
GHYTVSYGTD SGEFSSVGED FYRNRSQPPP LETLGLDADE LILIPNGVQI FFVNPAGEVS 240
APSYPGYLRI VRFLDNSLDT VLNRPPGFLQ VCDWLYPLVP DRSPVLKCTV GAYMFPDTML 300
QAAGCFVGVV LSSELPEDDR ELFEDLLRQM SDLRLQANWN REEDEFQIPG RSSHPSEPPK 360
EASGTDVRQS SSSGSSIDQG SKDARHKGKR GKKTKDSSEE VNLSQIVPCE PSSEEKSKEL 420
PEWSEKVAHN ILSGASWVSW GLVKGAEFTG KAIQKGASKL RERIQPEEKP VEVSPAVTRG 480
LYIAKQATGG AAKVSQLLVD GVCTVANCVG KELAPHVKKH GSKLVPESLK RDKDGKSALD 540
GAMVVAASSV QGFSTVWQGL ECAAKCIVNN VSAETVQTVR YKYGHNAGEA THNAVDSAIN 600
VGLTAYNIDN IGIKAMVKKT AKQTGHTLLE DYQIVERPQR ESQGGATSTE GRRDIGKQVE 660
EEKPGAGKKD K 671 |
Gene Ontology | GO:0005811; C:lipid particle; IDA:MGI. GO:0005741; C:mitochondrial outer membrane; IEA:Compara. GO:0045202; C:synapse; IDA:MGI. GO:0060612; P:adipose tissue development; IMP:MGI. GO:0000910; P:cytokinesis; IMP:MGI. GO:0034389; P:lipid particle organization; IMP:MGI. GO:0030514; P:negative regulation of BMP signaling pathway; IMP:MGI. GO:0048698; P:negative regulation of collateral sprouting in absence of injury; IMP:MGI. GO:0050905; P:neuromuscular process; IMP:MGI. GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |