CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008667
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Central kinetochore subunit OKP1 
Protein Synonyms/Alias
 Outer kinetochore protein 1 
Gene Name
 OKP1 
Gene Synonyms/Alias
 YGR179C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
57LDVAPEAKSTQSKKSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Component of the central kinetochore, which mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. Required for establishing bipolar spindle- microtubule attachments and proper chromosome segregation. 
Sequence Annotation
 MOD_RES 70 70 Phosphoserine.  
Keyword
 Cell cycle; Cell division; Centromere; Chromosome; Coiled coil; Complete proteome; Kinetochore; Meiosis; Mitosis; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 406 AA 
Protein Sequence
MAADRDNFLQ NIENDSINNG QAMDLSPNRS SSESDSSILM NVNDIKTLRL DVAPEAKSTQ 60
SKKSLFYENS DDAEEGEIEE RTNKEEGQYH HKGSKQLRFE VGKESTGKLQ SHLSDGSATS 120
GEGNVRPWEF RKVIQAEYRE RLPRNYELKH WKKPSKIMIG SILRLLETNT VSALDSVFEK 180
YEKEMNQMTH GDNNEVKRIY SKKERLLEII LTKIKKKLRQ AKFPSRISER DLDIEYIYSK 240
RQFIQNRYSQ ELQNNERLEA ILSREQNLLE ETRKLCMNLK TNNKKRLTEK LIQKDLHPVL 300
NKAMEYTYGL ESTNGFMHPD GPVTFRNDSH ELNLMLNDPI KSTADVRLDK EEVLSLLPSL 360
KEYTKKSKEL KETMGQMISD SHEEEIKEVF VPHHESHQDK TEEDIH 406 
Gene Ontology
 GO:0000817; C:COMA complex; IDA:SGD.
 GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:SGD.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007126; P:meiosis; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS