CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038894
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 
Protein Synonyms/Alias
  
Gene Name
 Hsd3b2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
27IRMLVQEKELQEVRAacetylation[1]
37QEVRALDKVFRPETKacetylation[1]
44KVFRPETKEEFSKLQacetylation[1]
49ETKEEFSKLQTKAKVacetylation[1]
332SKFTFSYKKAQRDLGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 373 AA 
Protein Sequence
MPGWSCLVTG AGGFVGQRII RMLVQEKELQ EVRALDKVFR PETKEEFSKL QTKAKVTMLE 60
GDILDAQYLR RACQGISVVI HTAALIDVTG VNPRQTILDV NLKGTQNLLE ACVQASVPAF 120
IYCSTVDVAG PNSYKKIILN GHEEEHHEST WSNPYPYSKK MAEKAVLAAN GSILKNGGTL 180
HTCALRPMYI YGERSPFLSV MILAALKSKG ILNVTGKFSI ANPVYVGNVA WAHILAARGL 240
RDPKKSQNVQ GQFYYISDDT PHQSYDDLNY TLSKEWGLHL DSSWSLPLPL LYWLAFLLEI 300
VSFFLHPVYN YRPSFNRHLV TLSNSKFTFS YKKAQRDLGY KPLVSWEEAK QKTSEWIGTL 360
VEQHRETLDT KSQ 373 
Gene Ontology
 GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
 GO:0006694; P:steroid biosynthetic process; IEA:InterPro. 
Interpro
 IPR002225; 3Beta_OHSteriod_DH/Estase.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF01073; 3Beta_HSD 
SMART
  
PROSITE
  
PRINTS