| Tag | Content |
|---|
| CPLM ID | CPLM-001487 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kelch-like protein 18 |
Protein Synonyms/Alias | |
Gene Name | KLHL18 |
Gene Synonyms/Alias | KIAA0795; OK/SW-cl.74 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 36 | EEIRRQGKLCDVTLK | ubiquitination | [1] | | 43 | KLCDVTLKIGDHKFS | ubiquitination | [1] | | 48 | TLKIGDHKFSAHRIV | ubiquitination | [1] | | 138 | LRERLHPKNCLGVRQ | ubiquitination | [1] | | 261 | RDLVDEAKDYHLMPE | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | DOMAIN 66 105 BTB.
DOMAIN 140 242 BACK.
REPEAT 289 336 Kelch 1.
REPEAT 337 383 Kelch 2.
REPEAT 384 430 Kelch 3.
REPEAT 432 477 Kelch 4.
REPEAT 479 524 Kelch 5.
REPEAT 525 571 Kelch 6. |
Keyword | Alternative splicing; Complete proteome; Kelch repeat; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 574 AA |
Protein Sequence | MVEDGAEELE DLVHFSVSEL PSRGYGVMEE IRRQGKLCDV TLKIGDHKFS AHRIVLAASI 60
PYFHAMFTND MMECKQDEIV MQGMDPSALE ALINFAYNGN LAIDQQNVQS LLMGASFLQL 120
QSIKDACCTF LRERLHPKNC LGVRQFAETM MCAVLYDAAN SFIHQHFVEV SMSEEFLALP 180
LEDVLELVSR DELNVKSEEQ VFEAALAWVR YDREQRGPYL PELLSNIRLP LCRPQFLSDR 240
VQQDDLVRCC HKCRDLVDEA KDYHLMPERR PHLPAFRTRP RCCTSIAGLI YAVGGLNSAG 300
DSLNVVEVFD PIANCWERCR PMTTARSRVG VAVVNGLLYA IGGYDGQLRL STVEAYNPET 360
DTWTRVGSMN SKRSAMGTVV LDGQIYVCGG YDGNSSLSSV ETYSPETDKW TVVTSMSSNR 420
SAAGVTVFEG RIYVSGGHDG LQIFSSVEHY NHHTATWHPA AGMLNKRCRH GAASLGSKMF 480
VCGGYDGSGF LSIAEMYSSV ADQWCLIVPM HTRRSRVSLV ASCGRLYAVG GYDGQSNLSS 540
VEMYDPETDC WTFMAPMACH EGGVGVGCIP LLTI 574 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |