Tag | Content |
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CPLM ID | CPLM-023811 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | WD repeat domain phosphoinositide-interacting protein 4 |
Protein Synonyms/Alias | WIPI-4; WD repeat-containing protein 45 |
Gene Name | WDR45 |
Gene Synonyms/Alias | WDRX1; WDRXI4; WIPI4; JM5 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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146 | FDTRDNPKGLCDLCP | ubiquitination | [1] | 157 | DLCPSLEKQLLVFPG | ubiquitination | [1] | 226 | RLFDTQSKEKLVELR | ubiquitination | [1] |
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Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | REPEAT 4 42 WD 1. REPEAT 190 230 WD 2. REPEAT 235 274 WD 3. |
Keyword | Alternative splicing; Complete proteome; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 360 AA |
Protein Sequence | MTQQPLRGVT SLRFNQDQSC FCCAMETGVR IYNVEPLMEK GHLDHEQVGS MGLVEMLHRS 60 NLLALVGGGS SPKFSEISAV LIWDDAREGK DSKEKLVLEF TFTKPVLSVR MRHDKIVIVL 120 KNRIYVYSFP DNPRKLFEFD TRDNPKGLCD LCPSLEKQLL VFPGHKCGSL QLVDLASTKP 180 GTSSAPFTIN AHQSDIACVS LNQPGTVVAS ASQKGTLIRL FDTQSKEKLV ELRRGTDPAT 240 LYCINFSHDS SFLCASSDKG TVHIFALKDT RLNRRSALAR VGKVGPMIGQ YVDSQWSLAS 300 FTVPAESACI CAFGRNTSKN VNSVIAICVD GTFHKYVFTP DGNCNREAFD VYLDICDDDD 360 F 361 |
Gene Ontology | GO:0005737; C:cytoplasm; IBA:RefGenome. GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IBA:RefGenome. GO:0032266; F:phosphatidylinositol-3-phosphate binding; IBA:RefGenome. GO:0000045; P:autophagic vacuole assembly; IBA:RefGenome. |
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