CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Epsin-2 
Protein Synonyms/Alias
  
Gene Name
 Epn2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
107IFAIQTLKDFQYIDRubiquitination[1]
117QYIDRDGKDQGINVRubiquitination[1]
429QPASNAGKTTDAWGAubiquitination[1]
503SLTSASSKPSSARKTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 640 AA 
Protein Sequence
MTTSSIRRQM KNIVNNYSEA EIKVREATSN DPWGPSSSLM TEIADLTYNV VAFSEIMSMV 60
WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVAQQCRENI FAIQTLKDFQ YIDRDGKDQG 120
INVREKSKQL VALLKDEERL KVERVQALKT KERMAQVATG VGSNQITFGR GSSQPNLSTS 180
YSEQEYGKAG GSPASYHGSP EASLCPQHRT GAMLGQSEEL QPLSQRHPCL PHLGLASHPN 240
GDWAQPCLTC DRAARATSPR VSSELEQARP QTSGEEELQL QLALAMSREV AEQEERLRRG 300
DDLRLQMALE ESRRDTVKVP KKKEAKACCK PGSHSQQTTL LDLMDALPSS GPVTQKTEPW 360
SAGASANQTN PWGGTVAPSN ITDPWPSFGT KPAASVDPWG VPTTASTQSV PKNSDPWAAS 420
QQPASNAGKT TDAWGAAKPS SASGSFELFS NFNGTVKDDF SEFDNLRTSK KPAESGASVP 480
PQDSRTTSPD LFESQSLTSA SSKPSSARKT PESFLGPNAA LVNLDSLVTK PAPPAQSLNP 540
FLAPGAAAPA PVNPFQVNQP QPLTLNQLRG SPVLGSSASF GSGPGVETVA PMTSVAPHSS 600
VGASGSSLTP LGPTAMNMVG SVGIPPSAAQ STGTTNPFLL 640 
Gene Ontology
 GO:0030128; C:clathrin coat of endocytic vesicle; IEA:InterPro.
 GO:0048568; P:embryonic organ development; IGI:MGI.
 GO:0006897; P:endocytosis; IEA:InterPro.
 GO:0001701; P:in utero embryonic development; IGI:MGI.
 GO:0007219; P:Notch signaling pathway; IGI:MGI. 
Interpro
 IPR008942; ENTH_VHS.
 IPR027319; Epsin-2_metazoa.
 IPR013809; Epsin-like_N.
 IPR001026; Epsin_dom_N.
 IPR003903; Ubiquitin-int_motif. 
Pfam
 PF01417; ENTH 
SMART
 SM00273; ENTH
 SM00726; UIM 
PROSITE
 PS50942; ENTH
 PS50330; UIM 
PRINTS