CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040555
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Pericentrin 
Protein Synonyms/Alias
  
Gene Name
 Pcnt 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1931AVAPSAGKHHAERTAacetylation[1]
2303GRAVLDGKEKELKVVacetylation[2]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2916 AA 
Protein Sequence
MEDEQEQRRR KVEAGRAKLA NFRQRKTKGD CPNSKKKTAK RKGSAVHASV QEEGSVATPN 60
SELPQGGAVF ESPSCSNTLE GTRGASAAQE QEDCELDVTD LQGQQQTQPP PPQTAHSLEL 120
EALRLSLNNM HTAQLELTQA NLQKEKETAL TELREMLNGR RAQELALLQS RQQCELELLR 180
EQHAREKEEM ALRSGQEAAE LKEKLRSEME KNAQTIETLK QDWESERELC LENLRQELSL 240
KHQSEMEGLQ SQFQKELSEQ KVELEKIFQA KHEAEVSLKN LEAQHQAAIK KLQEDLQSEH 300
CQYLQDLEQK FREKEKAKEL ELETLQASYE DLKAQSQEEI RLLWSQLESM KTNREELNGS 360
WDPVLAQASH LEELEHLRSG FAQQQQQERA QHESELEHLR VYFEKKLKDA EKTYQEDLTV 420
FQQRLQEARE DSLESTEISS SCVLPEETSG REGKEPPDPL DLQLGQPKVQ ESLVEDCQVK 480
LSKAEEKIQQ MKEEFQKKEA EWELSREELK REAEERLASM FLELREKAES EKLSIISRFE 540
HRESSMRHLQ DQQAAQILDL ERSLMEQQGH LRQLEQELTR DDLLPCSQCG QEPAMAQEEK 600
NGALLREKED CALQLLMAQN RFLEERKEIM EKFAKEQDAF LRDAQEKHNH ELQLLQQGHQ 660
QQLLALRMEL ETKHRSELTE QLASSESRRQ ALLETHVAEL QVKHNAEISA LEKRHLSNLD 720
ELESCYVADV QTIRDEHQQA LELLRAELEE QLQKKESCHR EMLTQELENL KRQHAEELQS 780
VRDSLRMEMS AQHIENGKGP AADLQGAHQQ DPAMALHNEG HLLVEDGDAV LRSVDAEGLL 840
HQAGPQELGD AHTVEMQKSQ AELAKPQELQ ASQDQVAQVR DKVFLLNREL EECRAELEQL 900
QQRRERENQE GTTLICMLRA DLELAQGEGK ALRDALRRLL DLFGDTLKAA VTLKSRISER 960
AGLLLDHEDA ADTSDARLAA AALGDMWSDE GLLEIDRTLP EGAETSSVCE ISSHVCESFF 1020
ISPENTLDCE QPIRRVYQSL STAVEGLLEM ALDSSKQLEE ARQLHRCVER EFRHRNEEMA 1080
QAMQKQQELL ERLREESAAK DRLALELHTA KGLLEGFKVE KVDLQEALGK KEESEQQLIL 1140
ELEDLRKQLQ QAARELLTLK EEKSVLWNQK ETLTNEAKER EAALQEEVES LTRVQWESRK 1200
QSEKDRATLL SQMRVLESEL EDQLVQHRGC AQLAEEVATL KQQLAALDKH LRSQRQFMDD 1260
QAAEREHERE EFQQEIQRLE GQLRQAARPR PPGPRDSQCV QLDEEVELLQ EKLREKLDGF 1320
NELVIKKDFA DQQLLIQEEE IKRLEETNAS IQRQMVQLQE ELEKQKKSME ELKEKEILKQ 1380
ENMGDLLLTT VSRSGLDEAG CPMLPQGSSS RGPEAQPDVT ERALLQHENE VVHRRNSEID 1440
ELKSLIENLQ ENQRQLQKDK AEEIEQLHEV IEKLQSELSL MGPKVHEVSD PQAGSLHSEL 1500
ACLRGEGLGG QALRSELQAA QAAKEVFGQL LADQAHGHSQ ALEALQQRLQ DAEEVAARHL 1560
AELEHCVALR EAEVEAMASQ IQEFAATLKA KEAIIEQRDL EIDAVNKWKV SHSLELEAIL 1620
LALAHFRHAL EQQTCATPDE PPELRQLRVQ CARLSHQLQV LYRPFLKCRM QLDQHQPHVA 1680
SIGCANPCAD DELEQEGVSN RLALAPHSLA AQAKEELEDC PLGKANLMAQ VRQLQEELDH 1740
RVHSVASRDT NSETCKLQQP NLSENGPRNH CCNGEESKPS PPDDVLNIAK TTWDVIDIIK 1800
NQDLLVQVEM PDFPTQEKLT SQGGPFSSQA SGHSGSLLPE EAAEPQQDPV RALDLSSWSS 1860
PEVVRKDPSL EPQHSLPLTP GVGTVSLHSV DISPDWTDPL LQADVSGLLC YPGKSASGQA 1920
PLWAVAPSAG KHHAERTATE KDVEDFIVTS FDSQELLTSP SHELARRSDG SRKSDGPDIA 1980
MMLTLGSEGS ETPTTDLVAA AAAAVPFSRR FVQSPGAMKE KEIHAKQMKA LLQMVFDESH 2040
QILALSESQD PSSALNKGEP RDPLDGFPRD SQALSEVTTD KGEKESLETH LTWSEELLRA 2100
IQEVFAREQE KAELQPRPYG SNLGDYNSLV QRLEKVIQEQ GDPQKVQDHL CLSDRSSLLA 2160
EIQALRAQLR MTHLQNQEKL QQLCAALTST EARGSQREHQ LRRQVELLAY KVEQEKCIAN 2220
ELQKTLSKEQ ETASDVRKRL VVEQNAVQDL KSELHACKQE NTSLLESLDK VQQEVLRLRY 2280
GHVTWSYCGT SSASAGRAVL DGKEKELKVV LEELESERGK GQALQAQQEE QQLRYLQREG 2340
QSSRALEELK LSLEKQLAQN NQLCVALKHE RAAKDNLQKE LQIEASRCEA LLAQEKGQLS 2400
ELQKSLEAER SRSLELSEAL QHERLLTEQL SRNSQEACAR QETQVQHALL RKLKAEKTRA 2460
LELEAMLEKV QKQAAHTQQQ LEAQAQERCV ELRREKEREL EIQRQRDEHK IEQLQRLVRE 2520
LRWKEEVSGG NGPCRGSPGR GSLERDQFQE QQQELEKIRQ QLLCAAGLLT SFTNHTVDRT 2580
IKDWTSSNEK AVSSLMRTLE ELKSELSMPT SFQKKMTAEL QVQLMNELLS DNDALTKAVG 2640
MATREKAELC RTVSRLEKTL KHHTQKGCVL NRQSKSSLKQ DGTDLQSSLR HSDPEWHSQT 2700
TSGDTNTCNI KMEKLYLHYL RAESFRKALI YQKKYLLLLI GGFQDSEQET LSMIAHLGVF 2760
PSKADKKITM SRPFTKFRTA VRVVIAVLRL RFLVKKWQEV DRKGALVHPK STRHGHRTSQ 2820
RQRSPSGPRA SLPTRDTSSG PTKASRHSPR SAAAGSPGKE RSTSTPSSRL ERSLTASQDP 2880
EHSLTEYIHH LEMIQQRLGG LPPDSTQKSC HQKIKQ 2916 
Gene Ontology
 GO:0005814; C:centriole; IDA:MGI.
 GO:0045171; C:intercellular bridge; IDA:MGI.
 GO:0006915; P:apoptotic process; IMP:MGI.
 GO:0048854; P:brain morphogenesis; IMP:MGI.
 GO:0021696; P:cerebellar cortex morphogenesis; IMP:MGI.
 GO:0042384; P:cilium assembly; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0035108; P:limb morphogenesis; IMP:MGI.
 GO:0035264; P:multicellular organism growth; IMP:MGI.
 GO:0061351; P:neural precursor cell proliferation; IMP:MGI.
 GO:0001764; P:neuron migration; IMP:MGI.
 GO:0021772; P:olfactory bulb development; IMP:MGI.
 GO:0007051; P:spindle organization; IDA:MGI. 
Interpro
 IPR019528; PACT_domain.
 IPR024151; Pericentrin. 
Pfam
 PF10495; PACT_coil_coil 
SMART
  
PROSITE
  
PRINTS