UniProt Accession

 APOL6_HUMAN; Q9BWW8; Q5R3S1; Q658J1; Q8IXX6; Q9UGG1 

Genbank Protein ID

 AY014879; AY358210; CR456381; AL834420; Z79996; BC038950; BC047864 

Genbank Nucleotide ID

 AAK07724.1; AAQ88577.1; CAG30267.1; CAH56356.1; CAI18758.1; AAH38950.2; AAH47864.1 

Protein Name

 Apolipoprotein L6 

Protein Synonyms/Alias

 Apolipoprotein L-VI; ApoL-VI 

Gene Name

 APOL6 

Gene Synonyms/Alias

 UNQ3095/PRO21341 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
160	DREDEEEKADYVTAA	ubiquitination	[1]
190	KNVRAFWKLRANPRL	ubiquitination	[1]
231	GTTLAMTKNARVLGG	ubiquitination	[1, 2, 3]
266	LKEGARTKFAEELRA	ubiquitination	[1, 3]
274	FAEELRAKALELERK	acetylation	[3]
274	FAEELRAKALELERK	ubiquitination	[1]
281	KALELERKLTELTQL	ubiquitination	[1]
290	TELTQLYKSLQQKVR	ubiquitination	[1, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles. 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Lipid transport; Polymorphism; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 343 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; NAS:UniProtKB.
 GO:0005576; C:extracellular region; IEA:InterPro.
 GO:0008289; F:lipid binding; IEA:InterPro.
 GO:0005319; F:lipid transporter activity; NAS:UniProtKB.
 GO:0042157; P:lipoprotein metabolic process; IEA:InterPro. 

Interpro

 IPR008405; ApoL. 

Pfam

 PF05461; ApoL 

SMART

  

PROSITE

  

PRINTS