CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025567
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kcnj10 protein 
Protein Synonyms/Alias
  
Gene Name
 Kcnj10 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
67AKMTSVAKVYYSQTTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Ion channel; Ion transport; Membrane; Potassium; Potassium transport; Transmembrane; Transmembrane helix; Transport; Voltage-gated channel. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 440 AA 
Protein Sequence
PRPARPRPRP PDKPLSDSSS GFKSLGPACR TAPLAAPARP VCSSVPLPRD LSEQPLHLRA 60
KMTSVAKVYY SQTTQTESRP LVAPGIRRRR VLTKDGRSNV RMEHIADKRF LYLKDLWTTF 120
IDMQWRYKLL LFSATFAGTW FLFGVVWYLV AVAHGDLLEL GPPANHTPCV VQVHTLTGAF 180
LFSLESQTTI GYGFRYISEE CPLAIVLLIA QLVLTTILEI FITGTFLAKI ARPKKRAETI 240
RFSQHAVVAS HNGKPCLMIR VANMRKSLLI GCQVTGKLLQ THQTKEGENI RLNQVNVTFQ 300
VDTASDSPFL ILPLTFYHVV DESSPLKDLP LRSGEGDFEL VLILSGTVES TSATCQVRTS 360
YLPEEILWGY EFTPAISLSA SGKYIADFSL FDQVVKVASP SGLRDSTVRY GDPEKLKLEE 420
SLREQAEKEG SALSVRISNV 440 
Gene Ontology
 GO:0016323; C:basolateral plasma membrane; IDA:MGI.
 GO:0005887; C:integral to plasma membrane; IC:MGI.
 GO:0005242; F:inward rectifier potassium channel activity; IMP:MGI.
 GO:0007628; P:adult walking behavior; IMP:MGI.
 GO:0022010; P:central nervous system myelination; IMP:MGI.
 GO:0051935; P:L-glutamate uptake involved in synaptic transmission; IMP:MGI.
 GO:0055075; P:potassium ion homeostasis; IMP:MGI.
 GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.
 GO:0060075; P:regulation of resting membrane potential; IMP:MGI.
 GO:0007601; P:visual perception; IMP:MGI. 
Interpro
 IPR014756; Ig_E-set.
 IPR016449; K_chnl_inward-rec_Kir.
 IPR003269; K_chnl_inward-rec_Kir1.2.
 IPR013518; K_chnl_inward-rec_Kir_cyto. 
Pfam
 PF01007; IRK 
SMART
  
PROSITE
  
PRINTS
 PR01322; KIR12CHANNEL.
 PR01320; KIRCHANNEL.