| Tag | Content |
|---|
| CPLM ID | CPLM-010581 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation factor Tu, mitochondrial |
Protein Synonyms/Alias | |
Gene Name | Tufm |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 79 | TLTAAITKILAEGGG | acetylation | [1] | | 88 | LAEGGGAKFKKYEEI | acetylation | [1] | | 90 | EGGGAKFKKYEEIDN | acetylation | [1] | | 91 | GGGAKFKKYEEIDNA | acetylation | [1] | | 238 | LGVKSVQKLLDAVDT | acetylation | [1] | | 256 | VPTRDLEKPFLLPVE | acetylation | [1] | | 342 | RRGLVMVKPGSIQPH | acetylation | [1] | | 361 | AQVYILSKEEGGRHK | acetylation | [1] | | 405 | AMPGEDLKLSLILRQ | acetylation | [1] | | 418 | RQPMILEKGQRFTLR | acetylation | [1] | | 447 | PAMTEEDKNIKWS** | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity). |
Sequence Annotation | NP_BIND 64 71 GTP (By similarity).
NP_BIND 126 130 GTP (By similarity).
NP_BIND 181 184 GTP (By similarity).
MOD_RES 79 79 N6-acetyllysine (By similarity).
MOD_RES 88 88 N6-acetyllysine (By similarity).
MOD_RES 256 256 N6-acetyllysine (By similarity).
MOD_RES 418 418 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Complete proteome; Elongation factor; GTP-binding; Mitochondrion; Nucleotide-binding; Protein biosynthesis; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 452 AA |
Protein Sequence | MAAATLLRAT PRFSGLCASP TPFLQGRLRP LKAPASPFLC RGLAVEAKKT YVRDKPHVNV 60
GTIGHVDHGK TTLTAAITKI LAEGGGAKFK KYEEIDNAPE ERARGITINA AHVEYSTAAR 120
HYAHTDCPGH ADYVKNMITG TAPLDGCILV VAANDGPMPQ TREHLLLAKQ IGVEHVVVYV 180
NKADAVQDSE MVELVELEIR ELLTEFGYKG EETPVIVGSA LCALEQRDPE LGVKSVQKLL 240
DAVDTYIPVP TRDLEKPFLL PVESVYSIPG RGTVVTGTLE RGILKKGDEC ELLGHNKNIR 300
TVVTGIEMFH KSLERAEAGD NLGALVRGLK REDLRRGLVM VKPGSIQPHQ KVEAQVYILS 360
KEEGGRHKPF VSHFMPVMFS LTWDMACRVI LPPGKELAMP GEDLKLSLIL RQPMILEKGQ 420
RFTLRDGNKT IGTGLVTDVP AMTEEDKNIK WS 452 |
Gene Ontology | GO:0042645; C:mitochondrial nucleoid; IEA:Compara. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW. GO:0006184; P:GTP catabolic process; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |