CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011398
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DOCK-like protein YLR422W 
Protein Synonyms/Alias
  
Gene Name
 YLR422W 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
512GLINKIIKDSSEGVSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
  
Sequence Annotation
 DOMAIN 1410 1824 DHR-2.  
Keyword
 Complete proteome; Cytoplasm; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1932 AA 
Protein Sequence
MSQQDSQRWL PTDRLIYGVL VKSFLPLQRY PELVYENSNY ANVYVGAEVY VFEESVDKKW 60
CRAYQCLRPF PEEFISNMNS ANDVLPDVKP KVVIFPRKYV HFEAEKAVST MPFFKAPSAE 120
DFKPLISKEC ESRSFCDSLY VSSTDDISTG KPRKTPRPPF PFFRYQKRSF KDEMGPILSL 180
ISSHVYSMYS IGEFSIYRKM IKLYYDLDTI RFRLSMNLTT EAEKINLIRA ATSLRTKIAK 240
FLSSTYRKNK LIANSTPRNP DPYGFEGIFA RDIDTGELLS YEIDKLRTLV SSSMLCGLTN 300
NFPTVPVVES DDESSSNGLF GTVRSSILVN LKDLAWDPSI SDPKYQDLSI CVYLRTKDEV 360
LTESFTMTKS SNMESALDEI PAMLFKNILE TIVHKNKVYL VVVLKETIAI TTETAPEISS 420
YNISTEESSS HSPFSPFNSS TENKIDHVKK GLAAGVINIS PVFKFYNGLS VANKAQRFNL 480
YLYSSDSSDS QNFNSSKDAD LGWGGLINKI IKDSSEGVSV NPRAVSLSVT VKEIIGKQEA 540
EKVLSTSLVP IRSIPTYFYD TMFSQAERIY LNLGRVSLYG LPAADTNIEN VTVQISCRNK 600
AVKFCKNKLE ERSGDWKFVS VRPNESIGES IRIEGVENMN EDETLRVLVY LNGFLMAKSN 660
IHIKKKNEII EYRKGTVFQI MSSKSVPLIH LELEASYFGR RYNINPAITN FLVLQTKNVE 720
FDQQLKEHYS VTLKQLNNVS FKDLLKHFDT ILAHYLLLLE SVNEATDKKG PSSSLPNIVF 780
SEFVKFLNLM LTHQENSRYW FNRLYKKVMS KELECPNVAP ILIKHMTTIF DRSHSSWTRT 840
GTAICRTILY IIVLAIGSSH SDEMPNFSHF FRSLHKFLML ADEPIMADQI LLIESIPSML 900
ETMTNHCKVE DLVRFAIGLF ECCQEKEMNQ KMYSRPLSVR EEEYLNTKFN CLLKLINKKV 960
LQNYLTNTES VDKLRLQFLS KTLEWLLTPY TPGDDKCFHV ESLRLVNSVF ITIIEDYKFD 1020
MLQRNLIRLL PYLCKSFVHL RRYCKKARLM RPRRVFTMLF PREIPCNYIP VDSIVNDEVV 1080
VEVLLELAII ICEITKIASS RFPSYQSFSE IINLCDKDTL FQSNFYSRQI TNENVYTITK 1140
TVFLFFKQDW FPGMKWLGVS ALLGRSSLIL LSLCKDYIIE NNSPSPSKES EKRVDMRLWA 1200
EYVKVILLVS NHKSASLTKL AITPRKAVYL ISGDLKKISA YILNECWDAL ATGHYNITYA 1260
KKYGLGALSD CQFELFVHNQ FLIREIFIFA FHRHIDATRI CCKILWGLGL NFWRIFGSLQ 1320
PAVNACIPEL FSAYQIGKLR LNDYELERFV SCLFFMMHVP DSDTFFPACM DFLRDLLGFL 1380
HIVNEIYKIP NQEEFDDDRT ARHIEMFEYL LEANRPELFH KMIYDLFIHF IQKKDFVQAA 1440
LSLELLAGTY AWDSNDTLEA ISFPPLPEQS SFERKEYLLK ESARNFSRGQ KPEKALAVYK 1500
DLIKAYDEIN YDLNGLAFVH DQIAGIYTRL QSIDRLVPTY FKVSFMGFGF PKSLRNKSFV 1560
FEGLPFEHIT SMHDRLLRSY HGSNIVHSQE EVDMLLMNPP MGKYIHVASV EPCLSISDNY 1620
NSSDKKSSIN NKVRMYIENR DLRTFSNSRR LPGAKGVTDL WVEEYTYHTM NTFPTLMNRS 1680
EIVKVTKSKL SPLENAIRSL QVKIQELYGL ENMCNKTLKD HGDVNDLFTE LSTNITGTIS 1740
APVNGGISQY KAFLEPSTSK QFSTDDLGRL TLAFDELVAV LGRCLTLHAE LLPSKDLKPS 1800
HDLLVRLFEE NFAEEIERYS RTLSEANRSR NNMITARIIS HKNPNKKASF SGRDHHTSGS 1860
NHSQFVLEHS DSFGPNSLLF GKYLTRTLSH SSTTSSLDKS GIVSGTSSTF LAGSQPNTNT 1920
DSQHKHDYSH SG 1932 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027357; DHR-2.
 IPR026791; DOCK.
 IPR010703; DOCK_C. 
Pfam
 PF06920; Ded_cyto 
SMART
  
PROSITE
 PS51651; DHR_2 
PRINTS