UniProt Accession

 E5RJN7_HUMAN; E5RJN7 

Genbank Protein ID

 AC018620; AC027018; AC100784 

Genbank Nucleotide ID

  

Protein Name

 Double-stranded RNA-binding protein Staufen homolog 2 

Protein Synonyms/Alias

  

Gene Name

 STAU2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
85	AEGEGNSKKLSKKRA	ubiquitination	[1, 2]
86	EGEGNSKKLSKKRAA	ubiquitination	[3]
111	PPLPVVEKPKLFFKK	ubiquitination	[3]
125	KRPKTIVKAGPEYGQ	ubiquitination	[1, 3]
148	AQIQQAKKEKEPDYV	ubiquitination	[3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 320 AA 

Protein Sequence

Gene Ontology

 GO:0003725; F:double-stranded RNA binding; IEA:InterPro. 

Interpro

 IPR001159; Ds-RNA-bd.
 IPR014720; dsRNA-bd-like_dom. 

Pfam

 PF00035; dsrm 

SMART

 SM00358; DSRM 

PROSITE

 PS50137; DS_RBD 

PRINTS